公开(公告)号：EP1678495A2

公开(公告)日：2006-07-12

申请号：EP04795939.0

申请日：2004-10-20

申请人： The Regents of the University of California

发明人： HELLER, Michael ,  SULLIVAN, Benjamin ,  ZLATANOVIC, Sanja ,  ESENER, Sadik ,  DEHLINGER, Dietrich

IPC分类号： G01N33/00

CPC分类号： G01N33/54346 ,  B82Y5/00 ,  B82Y10/00 ,  B82Y15/00 ,  B82Y30/00

摘要： The present invention relates to nanoscale transduction systems that produce reversible signals to facilitate detection. In one respect, the invention relates to the analysis of molecular binding events using higher order signaling nanoscale constructs, or 'nanomachines', that allow nanostructures to be individually detectable, even in the midst of high background noise. Such systems are particularly useful for improving the performance of rare target detection methods, as well as being generally useful in any field in which sensitivity, discrimination and confidence in detection are important.