专利检索 ap:("The Regents of the University of California" OR "Novartis AG") AND inv:"MCKENNA, Jeffrey" 第 1 页

1.

发明公开
COVALENT TARGETING OF E3 LIGASES 审中-公开

公开(公告)号：EP3863642A1

公开(公告)日：2021-08-18

申请号：EP19872219.1

申请日：2019-10-09

申请人： The Regents of the University of California , Novartis AG

发明人： SPRADLIN, Jessica , WARD, Carl, C. , NOMURA, Daniel, K. , SCHIRLE, Markus , TALLARICO, John, A. , MCKENNA, Jeffrey , MAIMONE, Thomas, John , HU, Xirui

IPC分类号： A61K31/5517 , A61K31/551 , C07D487/04 , C07D495/14

2.

发明公开
ANTIBODY CONJUGATES COMPRISING STING AGONIST 审中-公开

公开(公告)号：EP3615080A1

公开(公告)日：2020-03-04

申请号：EP18724677.2

申请日：2018-04-26

申请人： Novartis AG , Aduro Biotech, Inc. , Dubensky, Thomas W., Jr.

发明人： DUBENSKY, Thomas W. Jr. , BRUML, Jacob, Robert , CANHAM, Stephen , CHO, Charles, Y. , GAUTHIER, Kelsey , GLICKMAN, Laura, Hix , HAO, Xueshi , KANNE, David , KASIBHATLA, Shailaja , KATIBAH, George, Edwin , LE, Thanh Ngoc, Lan , LEONG, Justin , MCKENNA, Jeffrey , MCWHIRTER, Sarah , NDUBAKU, Chudi Obioma , OU, Weijia , SUNG, Leonard , TRIA, George, Scott , UNO, Tetsuo , WU, Tom, Yao-hsiang , WAN, Yongqin , DUBENSKY, Thomas W. Jr.

IPC分类号： A61K47/68 , C07H21/00 , A61P33/00

3.

发明公开
AUTOTAXIN INHIBITORS 审中-公开
标题翻译： AUTOTAXINHEMMER

公开(公告)号：EP3022201A1

公开(公告)日：2016-05-25

申请号：EP14766209.2

申请日：2014-07-16

申请人： Novartis AG

发明人： BAETTIG, Urs , BEATTIE, David , LEGRAND, Darren Mark , LISTER, Andrew Stuart , MCKENNA, Jeffrey , PEARCE, David William , SANDHAM, David Andrew , STANLEY, Emily , STEWARD, Oliver Ross , THOMSON, Christopher

IPC分类号： C07D403/12 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D257/04 , A61K31/41 , A61P35/00

CPC分类号： C07D401/12 , A61K45/06 , C07D257/04 , C07D403/12 , C07D405/12 , C07D407/12 , C07D413/12 , C07D417/12

摘要： The present invention relates to novel compounds that are autotaxin inhibitors, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in diseases and disorders mediated by autotaxin.

摘要翻译： 本发明涉及自体贴剂抑制剂的新型化合物，其制备方法，药物组合物和含有它们的药物及其在自体吸收素介导的疾病和病症中的用途。

4.

发明授权
TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL 有权
标题翻译：三环化合物抑制CFTR通道的

公开(公告)号：EP2935278B1

公开(公告)日：2017-03-15

申请号：EP13826625.9

申请日：2013-12-17

申请人： Novartis AG

发明人： AHMED, Mahbub , ASHALL-KELLY, Alexander , GUERITZ, Louisa , MCKENNA, Jeffrey , MCKENNA, Joseph , MUTTON, Simon , PARMAR, Rakesh , SHEPHERD, Jon , WRIGHT, Paul

IPC分类号： C07D487/14 , C07D487/04 , C07D495/14 , A61K31/519 , A61P13/12 , A61P1/12

CPC分类号： C07D513/14 , A61K31/519 , A61K31/542 , A61K31/55 , A61K45/06 , C07D471/14 , C07D487/04 , C07D487/14 , C07D487/22 , C07D495/14 , C07D513/00

5.

发明公开
TRICYCLIC COMPOUNDS AS CFTR INHIBITORS 有权
标题翻译： TRICYCLISCHE VERBINDUNGEN ALS CFTR-INHIBITOREN

公开(公告)号：EP2935277A1

公开(公告)日：2015-10-28

申请号：EP13826624.2

申请日：2013-12-17

申请人： Novartis AG

发明人： AHMED, Mahbub , ASHALL-KELLY, Alexander , BLOOMFIELD, Graham Charles , GUERITZ, Louisa , MCKENNA, Jeffrey , MCKENNA, Joseph , MUTTON, Simon , PARMAR, Rakesh , SHEPHERD, Jon , WRIGHT, Paul

IPC分类号： C07D487/14 , C07D498/14 , A61K31/519 , A61K31/5383 , A61P1/12

CPC分类号： C07D487/14 , A61K31/519 , A61K31/5383 , A61K31/553 , A61K45/06 , C07D498/14

摘要： The present invention provides a CFTR inhibitor of formula (I) or a pharmaceutically acceptable salt thereof; and its therapeutic uses, e.g. in the treatment of diarrhea. The present invention further provides a combination of pharmacological active agents and a pharmaceutical composition.

摘要翻译： 本发明提供式I化合物或其药学上可接受的盐; 及其治疗用途。本发明还提供药理活性剂和药物组合物的组合。

6.

发明公开
BIS 2'-5'-RR-(3'F-A)(3'F-A) CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF 审中-公开

公开(公告)号：EP3615548A1

公开(公告)日：2020-03-04

申请号：EP18725304.2

申请日：2018-04-26

申请人： Aduro Biotech, Inc. , Novartis AG

发明人： LEONG, Justin , NDUBAKU, Chudi Obioma , MCKENNA, Jeffrey

IPC分类号： C07H21/02 , A61K31/7084 , A61K47/26 , A61P35/00

7.

发明公开
LOCKED NUCLEIC ACID CYCLIC DINUCLEOTIDE COMPOUNDS AND USES THEREOF 审中-公开

公开(公告)号：EP3507367A1

公开(公告)日：2019-07-10

申请号：EP17824754.0

申请日：2017-07-01

申请人： Aduro BioTech, Inc. , Novartis AG

发明人： KANNE, David, Braun , NDUBAKU, Chudi, Obioma , BRUML, Jacob, Robert , LE, Thanh Ngoc Lan , MCKENNA, Jeffrey , TRIA, George, Scott , CANHAM, Stephen

IPC分类号： C12N15/113

8.

发明授权
PYRAZOLO[5,1B]OXAZOLE DERIVATIVES AS CRF-1 RECEPTOR ANTAGONISTS 有权
标题翻译：吡唑并[5,1B-]恶唑衍生物作为CRF-1受体拮抗剂

公开(公告)号：EP2531510B1

公开(公告)日：2014-07-23

申请号：EP11701662.6

申请日：2011-01-28

申请人： Novartis AG

发明人： DEVEREUX, Nicholas James , MCKENNA, Jeffrey

IPC分类号： C07D491/048 , A61K31/4162 , A61P1/00 , A61P25/00 , A61P39/00

CPC分类号： C07D491/048

9.

发明公开
3-SPIROCYCLIC PIPERIDINE DERIVATIVES AS GHRELIN RECEPTOR AGONISTS 审中-公开
标题翻译： 3-螺环哌啶ALS生长素释放肽受体激动剂

公开(公告)号：EP2714690A1

公开(公告)日：2014-04-09

申请号：EP12727947.9

申请日：2012-05-25

申请人： Novartis AG

发明人： AMBARKHANE, Ameet Vijay , BHALAY, Gurdip , BECKETT, Martin , DALE, James , HAMADI, Ahmed , MAZZACANI, Alessandro , MCKENNA, Jeffrey , THOMSON, Christopher

IPC分类号： C07D471/10 , C07D487/10 , A61K31/438 , A61P1/00

CPC分类号： C07D471/10 , A61K31/407 , A61K31/435 , A61K31/55 , A61K45/06 , C07D487/10

摘要： The invention relates to derivatives of formula (I), wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions comprising such derivatives; such derivatives as a medicament; such derivatives for the treatment of a disorder or a disease mediated by the ghrelin receptor.

10.

发明公开
PYRAZOLO [5,1-B]OXAZOLE DERIVATIVES AS CRF1 ANTAGONISTS 审中-公开
标题翻译：吡唑并[5,1-B]恶唑AS CRF1拮抗剂

公开(公告)号：EP2328902A1

公开(公告)日：2011-06-08

申请号：EP09804561.0

申请日：2009-08-04

申请人： Novartis AG

发明人： BRUCE, Ian , CULSHAW, Andrew James , DEVEREUX, Nicholas James , GESSIER, François , MCKENNA, Jeffrey , NEEF, James , OAKMAN, Helen Elizabeth

IPC分类号： C07D498/04 , A61K31/424 , A61P43/00

CPC分类号： C07D498/04

摘要： There are described pyrazolo [5.1 -b] oxazole derivatives of structure I useful as corticotropin releasing factor (CRF
1 ) receptor antagonists.