公开(公告)号：EP2383343A3

公开(公告)日：2012-01-25

申请号：EP11153574.6

申请日：2005-03-03

申请人： The Research Foundation for Microbial Diseases of Osaka University

发明人： Nagaike, Kazuhiro ,  Mori, Yasuko ,  Gomi, Yasuyuki ,  Takahashi, Michiaki ,  Yamanishi, Kouichi

IPC分类号： C12N15/38 ,  A61K39/25 ,  A61P31/22 ,  C12N5/10 ,  C12N7/00 ,  C07K14/04 ,  C12N7/04

CPC分类号： A61K39/25 ,  A61K39/12 ,  A61K2039/5254 ,  C07K14/005 ,  C12N7/00 ,  C12N2710/16722 ,  C12N2710/16734 ,  C12N2710/16761 ,  C12N2800/50 ,  C12N2820/55

摘要： A recombinant varicella-zoster virus; a process for producing the same; a pharmacological composition containing recombinant varicella-zoster virus; a vector containing a genomic gene of varicella-zoster virus and BAC vector sequence; cells containing the above vector; a fragment capable of homologous recombination with a genome of varicella-zoster virus; and a nucleic acid cassette containing the BAC vector sequence. For these, there is provided a process for producing recombinant varicella-zoster virus, comprising use of the BAC vector sequence.

公开(公告)号：EP2383343A2

公开(公告)日：2011-11-02

申请号：EP11153574.6

申请日：2005-03-03

申请人： The Research Foundation for Microbial Diseases of Osaka University

发明人： Nagaike, Kazuhiro ,  Mori, Yasuko ,  Gomi, Yasuyuki ,  Takahashi, Michiaki ,  Yamanishi, Kouichi

IPC分类号： C12N15/38 ,  A61K39/25 ,  A61P31/22 ,  C12N5/10 ,  C12N7/00 ,  C07K14/04 ,  C12N7/04

CPC分类号： A61K39/25 ,  A61K39/12 ,  A61K2039/5254 ,  C07K14/005 ,  C12N7/00 ,  C12N2710/16722 ,  C12N2710/16734 ,  C12N2710/16761 ,  C12N2800/50 ,  C12N2820/55

摘要： A recombinant varicella-zoster virus; a process for producing the same; a pharmacological composition containing recombinant varicella-zoster virus; a vector containing a genomic gene of varicella-zoster virus and BAC vector sequence; cells containing the above vector; a fragment capable of homologous recombination with a genome of varicella-zoster virus; and a nucleic acid cassette containing the BAC vector sequence. For these, there is provided a process for producing recombinant varicella-zoster virus, comprising use of the BAC vector sequence.

摘要翻译： 重组水痘带状疱疹病毒; 其制造方法; 含有重组水痘带状疱疹病毒的药物组合物; 含有水痘带状疱疹病毒和BAC载体序列的基因组基因的载体; 含有上述载体的细胞; 能够与水痘带状疱疹病毒基因组同源重组的片段; 和含有BAC载体序列的核酸盒。 为此，提供了一种生产重组水痘带状疱疹病毒的方法，其包括使用BAC载体序列。