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1.
公开(公告)号:EP4277619A1
公开(公告)日:2023-11-22
申请号:EP22703250.5
申请日:2022-01-14
发明人: BOLLONG, Michael , SCHULTZ, Peter , SHAO, Sida , CHATTERJEE, Arnab , CHEN, Jian , ZHANG, Nan
IPC分类号: A61K31/403 , A61K31/4985 , A61K31/522 , A61K31/69 , A61P1/00 , A61P3/00 , A61P7/00 , A61P9/00 , A61P11/00 , A61P13/00 , A61P17/00 , A61P19/00 , A61P21/00 , A61P25/00 , A61P27/00
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公开(公告)号:EP4103618A2
公开(公告)日:2022-12-21
申请号:EP21753017.9
申请日:2021-02-11
发明人: JOSEPH, Sean , LEI, Lei , SHEN, Weijun , WANG, Feng , SCHULTZ, Peter
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公开(公告)号:EP1490483B1
公开(公告)日:2015-06-03
申请号:EP02725743.5
申请日:2002-04-19
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5.SELECTIVE INCORPORATION OF 5-HYROXYTRYPOPHAN INTO PROTEINS IN MAMMALIAN CELLS 审中-公开
标题翻译: 5 - 羟色蛋白哺乳动物细胞选择性诱导公开(公告)号:EP1725251A2
公开(公告)日:2006-11-29
申请号:EP04822141.0
申请日:2004-12-16
发明人: ZHANG, Zhiwen , ALFONTA, Lital , SCHULTZ, Peter
摘要: This invention provides methods and compositions for incorporation of an unnatural amino acid into a peptide using an orthogonal aminoacyl tRNA synthetase/tRNA pair. In particular, an orthogonal pair is provided to incorporate 5-hydroxy-L-tryptophan in a position encoded by an opal mutation.
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公开(公告)号:EP3983013A1
公开(公告)日:2022-04-20
申请号:EP20821831.3
申请日:2020-06-12
发明人: SCHULTZ, Peter , WANG, Feng , FANG, Ray, Changming , CAO, Yu, J. , SHEN, Weijun , LYU, Xiaoxuan , LEAR, Sam
IPC分类号: A61K39/395 , C07K16/28 , C07K16/30 , C07K16/32
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7.METHODS AND COMPOSITION FOR THE PRODUCTION OF ORTHOGANAL TRNA-AMINOACYLTRNA SYNTHETASE PAIRS 有权
标题翻译: 方法和组合物用于生产ORTHOGANALEN tRNA /氨酰-tRNA合成酶配对公开(公告)号:EP1456360B1
公开(公告)日:2015-06-03
申请号:EP02731454.1
申请日:2002-04-19
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公开(公告)号:EP2453921A2
公开(公告)日:2012-05-23
申请号:EP10800425.0
申请日:2010-07-13
发明人: JOHNSON, Kristen , JENNINGS, Lori , SCHULTZ, Peter
IPC分类号: A61K39/395
CPC分类号: A61K38/1891 , A61K31/728 , A61K38/00 , A61K47/60 , C07K14/515 , A61K2300/00
摘要: The present invention provides for methods and compositions for treating or preventing arthritis and joint injury.
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公开(公告)号:EP2453921B1
公开(公告)日:2015-05-27
申请号:EP10800425.0
申请日:2010-07-13
发明人: JOHNSON, Kristen , JENNINGS, Lori , SCHULTZ, Peter
IPC分类号: A61K39/395
CPC分类号: A61K38/1891 , A61K31/728 , A61K38/00 , A61K47/60 , C07K14/515 , A61K2300/00
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10.DIRECTED DIFFERENTIATION OF OLIGODENDROCYTE PRECURSOR CELLS TO A MYELINATING CELL FATE 审中-公开
标题翻译: FOR A少突胶质细胞PRE-MYELINIERUNGS细胞命运的细胞靶向分化公开(公告)号:EP2675893A1
公开(公告)日:2013-12-25
申请号:EP12747134.0
申请日:2012-02-17
IPC分类号: C12N5/00
CPC分类号: A61K31/5415 , A61K31/135 , A61K31/137 , A61K31/138 , A61K31/216 , A61K31/40 , A61K31/439 , A61K31/46 , A61K31/495 , A61K38/215 , A61K39/3955
摘要: The present invention provides methods of inducing differentiation of oligodendrocyte progenitor cells to a mature myelinating cell fate with a neurotransmitter receptor modulating agent. The present invention also provides methods of stimulating increased myelination in a subject in need thereof by administering said neurotransmitter receptor modulating agent. Methods of treating a subject having a demyelinating disease using a neurotransmitter receptor modulating agent are also provided.
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