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1.发明授权Orthogonal translation components for the in vivo incorporation of unnatural amino acids 有权对非天然氨基酸的体内掺入正交翻译组分
公开(公告)号：EP2380982B1
公开(公告)日：2014-07-16
申请号：EP11164983.6
申请日：2005-10-27
发明人： Alfonta, Lital , Schultz, Peter , Zeng, Huaqiang , Xie, Jianming , Wu, Ning , Wang, Jiangyun , Tsao, Meng-lin , Summerer, Daniel , Groff, Dan , Deiters, Alexander , Chittuluru, Jonathan, R. , Seyedsayamdost, Mohammad R. , Turner, James
CPC分类号： C12N9/93 , C12N15/1058 , C12P21/00 , C12P21/02
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2.发明公开Orthogonal translation components for the in vivo incorporation of unnatural amino acids 有权对非天然氨基酸的体内掺入正交翻译组分
公开(公告)号：EP2383340A3
公开(公告)日：2012-03-21
申请号：EP11165007.3
申请日：2005-10-27
发明人： Alfonta, Lital , Schultz, Peter , Zeng, Huaqiang , Xie, Jianming , Wu, Ning , Wang, Jiangyun , Tsao, Meng-lin , Summerer, Daniel , Groff, Dan , Deiters, Alexander , Chittuluru, Jonathan, R. , Seyedsayamdost, Mohammad R. , Turner, James
CPC分类号： C12N9/93 , C12N15/1058 , C12P21/00 , C12P21/02
摘要： The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate unnatural amino acids into proteins produced in eubacterial host cells such as E.coli, or in a eukaryotic host such as a yeast cell. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing unnatural amino acids, and translation systems.
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3.发明授权Orthogonal translation components for the in vivo incorporation of unnatural amino acids 有权用于体内并入非天然氨基酸的正交翻译组件
公开(公告)号：EP2383340B1
公开(公告)日：2014-07-16
申请号：EP11165007.3
申请日：2005-10-27
发明人： Alfonta, Lital , Schultz, Peter , Zeng, Huaqiang , Xie, Jianming , Wu, Ning , Wang, Jiangyun , Tsao, Meng-lin , Summerer, Daniel , Groff, Dan , Deiters, Alexander , Chittuluru, Jonathan, R. , Seyedsayamdost, Mohammad R. , Turner, James
CPC分类号： C12N9/93 , C12N15/1058 , C12P21/00 , C12P21/02
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4.发明公开Orthogonal translation components for the in vivo incorporation of unnatural amino acids 有权Orthogonale Translationskomponentenfürden In-Vivo-EinbaunichtnatürlicherAminosäuren
公开(公告)号：EP2383340A2
公开(公告)日：2011-11-02
申请号：EP11165007.3
申请日：2005-10-27
发明人： Alfonta, Lital , Schultz, Peter , Zeng, Huaqiang , Xie, Jianming , Wu, Ning , Wang, Jiangyun , Tsao, Meng-lin , Summerer, Daniel , Groff, Dan , Deiters, Alexander , Chittuluru, Jonathan, R. , Seyedsayamdost, Mohammad R. , Turner, James
CPC分类号： C12N9/93 , C12N15/1058 , C12P21/00 , C12P21/02
摘要： The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate unnatural amino acids into proteins produced in eubacterial host cells such as E.coli, or in a eukaryotic host such as a yeast cell. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing unnatural amino acids, and translation systems.
摘要翻译： 本发明涉及tRNA和氨酰-tRNA合成酶的正交对，其可以将非天然氨基酸掺入到在细菌宿主细胞如大肠杆菌或真核宿主如酵母细胞中产生的蛋白质中。 本发明提供了例如但不限于新的正交合成酶，用于鉴定和制备新合成酶的方法，用于产生含有非天然氨基酸的蛋白质的方法和翻译系统。
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5.发明公开Orthogonal translation components for the in vivo incorporation of unnatural amino acids 有权用于体内并入非天然氨基酸的正交翻译组件
公开(公告)号：EP2380982A1
公开(公告)日：2011-10-26
申请号：EP11164983.6
申请日：2005-10-27
发明人： Alfonta, Lital , Schultz, Peter , Zeng, Huaqiang , Xie, Jianming , Wu, Ning , Wang, Jiangyun , Tsao, Meng-lin , Summerer, Daniel , Groff, Dan , Deiters, Alexander , Chittuluru, Jonathan, R. , Seyedsayamdost, Mohammad R. , Turner, James
CPC分类号： C12N9/93 , C12N15/1058 , C12P21/00 , C12P21/02
摘要： The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate unnatural amino acids into proteins produced in eubacterial host cells such as E.coli , or in a eukaryotic host such as a yeast cell. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing unnatural amino acids, and translation systems.
摘要翻译： 本发明涉及正交对的tRNA和氨酰基tRNA合成酶，可以将非天然氨基酸并入在真细菌宿主细胞例如大肠杆菌，或在真核宿主中产生的蛋白质，如酵母细胞。 本发明提供例如但不限于新颖的正交合成酶，鉴定和制备新型合成酶的方法，生产含有非天然氨基酸的蛋白质的方法和翻译系统。
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