公开(公告)号：EP2304414A2

公开(公告)日：2011-04-06

申请号：EP09801077.0

申请日：2009-07-24

申请人： The Trustees of Princeton University

发明人： STURM, James, C. ,  AUSTIN, Robert ,  LOUTHERBACK, Kevin ,  MORTON, Keith ,  PUCHALLA, Jason

IPC分类号： G01N27/00

CPC分类号： B03B5/00 ,  B01L3/502753 ,  G01N27/44791 ,  G01N30/0005 ,  G01N30/6069 ,  G01N30/6095 ,  G01N2030/528

摘要： The disclosure relates to obstacle array devices (also known as bump array devices) for separating populations of particles by size. Improvements over previous obstacle array devices are realized by causing the fluid velocity profile across gaps between obstacles to be asymmetrical with respect to the plane that bisects the gap and is parallel to the direction of bulk fluid flow. Such asymmetry can be achieved by selecting the shape(s) of the obstacles bounding the gap such that the portions of the obstacles upstream from, downstream from, or bridging the narrowest portion of the gap are asymmetrical with respect to that plane. Improvements are also realized by using obstacles that have sharp edges bounding the gaps. Other improvements are realized by selecting obstacle shapes such that the critical particle dimensions defined by the gaps in two different fluid flow directions differ.

公开(公告)号：EP3196642A1

公开(公告)日：2017-07-26

申请号：EP17160810.2

申请日：2009-07-24

申请人： The Trustees of Princeton University

发明人： STURM, James C. ,  AUSTIN, Robert ,  LOUTHERBACK, Kevin ,  MORTON, Keith ,  PUCHALLA, Jason

IPC分类号： G01N30/00 ,  G01N30/60 ,  G01N27/447

CPC分类号： B03B5/00 ,  B01L3/502753 ,  G01N27/44791 ,  G01N30/0005 ,  G01N30/6069 ,  G01N30/6095 ,  G01N2030/528

摘要： The disclosure relates to obstacle array devices (also known as bump array devices) for separating populations of particles by size. Improvements over previous obstacle array devices are realized by causing the fluid velocity profile across gaps between obstacles to be asymmetrical with respect to the plane that bisects the gap and is parallel to the direction of bulk fluid flow. Such asymmetry can be achieved by selecting the shape(s) of the obstacles bounding the gap such that the portions of the obstacles upstream from, downstream from, or bridging the narrowest portion of the gap are asymmetrical with respect to that plane. Improvements are also realized by using obstacles that have sharp edges bounding the gaps. Other improvements are realized by selecting obstacle shapes such that the critical particle dimensions defined by the gaps in two different fluid flow directions differ.

摘要翻译： 本公开涉及用于按尺寸分离颗粒群体的障碍物阵列装置（也称为凸块阵列装置）。 通过使跨越障碍物之间的间隙的流体速度分布相对于平分间隙且平行于整体流体流动的方向的平面不对称来实现对先前障碍物阵列装置的改进。 这种不对称可以通过选择限定间隙的障碍物的形状来实现，使得障碍物的上游，下游或桥接间隙的最窄部分的部分相对于该平面不对称。 通过使用边界尖锐的障碍物也可以实现改进。 其他改进通过选择障碍物形状来实现，使得由两个不同流体流动方向上的间隙限定的临界颗粒尺寸不同。

公开(公告)号：EP2304414B1

公开(公告)日：2017-03-15

申请号：EP09801077.0

申请日：2009-07-24

申请人： The Trustees of Princeton University

发明人： STURM, James, C. ,  AUSTIN, Robert ,  LOUTHERBACK, Kevin ,  MORTON, Keith ,  PUCHALLA, Jason

IPC分类号： G01N30/00 ,  G01N30/60 ,  G01N27/447

CPC分类号： B03B5/00 ,  B01L3/502753 ,  G01N27/44791 ,  G01N30/0005 ,  G01N30/6069 ,  G01N30/6095 ,  G01N2030/528