专利检索 ap:("The Trustees of the University of Pennsylvania" OR "Kira Pharmaceuticals (US) LLC") AND inv:"MIWA, Takashi" 第 1 页

1.

发明公开
BI-FUNCTIONAL HUMANIZED ANTI-C5 ANTIBODIES AND FACTOR H FUSION PROTEINS AND USES THEREOF 审中-公开

公开(公告)号：EP3958901A1

公开(公告)日：2022-03-02

申请号：EP20795853.9

申请日：2020-04-24

申请人： The Trustees of the University of Pennsylvania , Kira Pharmaceuticals (US) LLC

发明人： SONG, Wenchao , MIWA, Takashi , GULLIPALLI, Damodar , SATO, Sayaka , TSUI, Ping , ZHU, Yingjie , ZHU, Xihua

IPC分类号： A61K39/395 , C07K16/18 , C07K16/46

2.

发明公开
HUMANIZED ANTI-C5 ANTIBODIES AND USES THEREOF 审中-公开

公开(公告)号：EP3846850A1

公开(公告)日：2021-07-14

申请号：EP19857639.9

申请日：2019-09-06

申请人： The Trustees of the University of Pennsylvania , Kira Pharmaceuticals (US) LLC

发明人： SONG, Wenchao , MIWA, Takashi , GULLIPALLI, Damodar , TSUI, Ping , SATO, Sayaka

IPC分类号： A61K39/395 , C07K16/18 , C07K16/46

3.

发明公开
ANTI-C5A ANTIBODIES AND USES THEREOF 审中-公开

公开(公告)号：EP3600421A1

公开(公告)日：2020-02-05

申请号：EP18772559.3

申请日：2018-03-23

申请人： The Trustees of The University of Pennsylvania

发明人： SONG, Wenchao , MIWA, Takashi , SATO, Sayaka , GULLIPALLI, Damodar

IPC分类号： A61K39/395 , A61K39/00 , A61K45/06 , C07K16/18 , C07K16/28 , C07K14/00

4.

发明公开
HUMANIZED ANTI-C5A ANTIBODIES AND USES THEREOF 审中-实审

公开(公告)号：EP4408890A1

公开(公告)日：2024-08-07

申请号：EP22875025.3

申请日：2022-09-28

申请人： The Trustees of the University of Pennsylvania , Kira Pharmaceuticals (Suzhou) Ltd.

发明人： TSUI, Ping , ZHANG, Jianjun , ZHU, Xihua , QI, Shigang , SONG, Wenchao , MIWA, Takashi , SATO, Sayaka , GULLIPALLI, Damodara Rao

IPC分类号： C07K16/28 , C12N15/13 , C12N15/85 , C12N5/10 , A61K39/395 , A61P11/06 , A61P19/02 , A61P27/02

CPC分类号： A61P11/06 , A61P19/02 , A61P27/02 , C07K16/18 , C07K2317/2420130101 , C07K2317/9220130101 , C07K2317/7620130101 , A61K2039/50520130101 , A61K2039/54520130101

5.

发明公开
ANTI-FACTOR D ANTIBODIES AND USES THEREOF 审中-公开

公开(公告)号：EP3580241A1

公开(公告)日：2019-12-18

申请号：EP18751478.1

申请日：2018-02-09

申请人： The Trustees of The University of Pennsylvania

发明人： SONG, Wenchao , ZHOU, Lin , SATO, Sayaka , MIWA, Takashi , GULLIPALLI, Damodar , GOLLA, Madhu

IPC分类号： C07K16/40

6.

发明公开
ANTI-C5 ANTIBODIES AND USES THEREOF 审中-公开

公开(公告)号：EP3592386A1

公开(公告)日：2020-01-15

申请号：EP18763099.1

申请日：2018-03-06

申请人： The Trustees of The University of Pennsylvania

发明人： SONG, Wenchao , SATO, Sayaka , MIWA, Takashi , GUILLIPALLI, Damodar

IPC分类号： A61K39/395 , C07K16/00 , C07K16/18 , C07K16/28 , C07K16/46 , C12N15/09

7.

发明公开
HUMANIZED ANTI-C5 ANTIBODIES AND FACTOR H FUSION PROTEINS AND USES THEREOF 审中-公开

公开(公告)号：EP4267612A1

公开(公告)日：2023-11-01

申请号：EP20966612.2

申请日：2020-12-25

申请人： The Trustees of the University of Pennsylvania , Kira Pharmaceuticals (Suzhou) Ltd.

发明人： SONG, Wenchao , MIWA, Takashi , SATO, Sayaka , GULLIPALLI, Damodara Rao , TSUI, Ping , ZHU, Xihua , ZHANG, Jianjun , XU, Yingying

IPC分类号： C07K16/18 , A61K39/395 , C07K19/00 , A61P37/00

8.

发明公开
COMPOSITION AND METHOD FOR TREATING COMPLEMENT-MEDIATED DISEASE 审中-公开

公开(公告)号：EP3359663A2

公开(公告)日：2018-08-15

申请号：EP16849709.7

申请日：2016-09-23

申请人： The Trustees of The University of Pennsylvania

发明人： SONG, Wenchao , GULLIPALLI, Damodar , MIWA, Takashi

IPC分类号： C12N9/88 , A61K38/51

CPC分类号： C07K14/472 , A61K48/00 , C12N2750/14143 , C12N2750/14171

摘要： A recombinant vector having an expression cassette comprising a modified human factor H (hfH) gene is provided, wherein said hfH gene encodes a hfH protein variant comprising SCR1-4, 19-20, and one or more of SCR7, SCR17 and/or SCR18. Also provided are pharmaceutical compositions containing this vector and uses therefor in treating AMD and/or other complement associated diseases.