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公开(公告)号：EP3439695A1
公开(公告)日：2019-02-13
申请号：EP17718216.9
申请日：2017-03-31
申请人： The U.S.A. as represented by the Secretary, Department of Health and Human Services , The University Of Maryland , Thomas Jefferson University
发明人： JOHNSON, Reed F. , SCHNELL, Matthias , HENSLEY, Lisa E. , WIRBLICH, Christoph , COLEMAN, Christopher M. , FRIEMAN, Matthew B.
IPC分类号： A61K39/12 , A61K39/205 , A61K39/215 , C12N7/04 , C12N15/86
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公开(公告)号：EP4104854A2
公开(公告)日：2022-12-21
申请号：EP22171378.7
申请日：2017-03-31
申请人： The United States of America as represented by the Secretary of the Department of Health and Human Services , The University Of Maryland , Thomas Jefferson University
发明人： JOHNSON, Reed, F. , SCHNELL, Matthias , HENSLEY, Lisa, E. , WIRBLICH, Christoph , COLEMAN, Christopher, M. , FRIEMAN, Matthew, B.
IPC分类号： A61K39/12 , A61K39/205 , A61K39/215 , C12N7/04 , C12N15/86
摘要： The present disclosure provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a coronavirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a coronavirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present disclosure provides a recombinant rabies virus vector comprising a nucleotide sequence encoding at least one coronavirus immunogenic glycoprotein fragment, as well as pharmaceutical compositions comprising the vaccine vectors.
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公开(公告)号：EP4104854A3
公开(公告)日：2023-03-08
申请号：EP22171378.7
申请日：2017-03-31
申请人： The United States of America as represented by the Secretary of the Department of Health and Human Services , The University Of Maryland , Thomas Jefferson University
发明人： JOHNSON, Reed, F. , SCHNELL, Matthias , HENSLEY, Lisa, E. , WIRBLICH, Christoph , COLEMAN, Christopher, M. , FRIEMAN, Matthew, B.
IPC分类号： A61K39/12 , A61K39/205 , A61K39/215 , C12N7/04 , C12N15/86
摘要： The present disclosure provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a coronavirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a coronavirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present disclosure provides a recombinant rabies virus vector comprising a nucleotide sequence encoding at least one coronavirus immunogenic glycoprotein fragment, as well as pharmaceutical compositions comprising the vaccine vectors.
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公开(公告)号：EP1768697B1
公开(公告)日：2010-06-02
申请号：EP05790962.4
申请日：2005-07-12
IPC分类号： C12N7/00 , C12N15/00 , C07K14/00 , A61K39/205
CPC分类号： C12N7/00 , A61K35/13 , C07K14/005 , C12N2760/20121 , C12N2760/20122 , C12N2760/20161
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