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公开(公告)号:EP2449096A1
公开(公告)日:2012-05-09
申请号:EP10793446.5
申请日:2010-07-05
CPC分类号: C07K14/005 , A61K2039/5258 , C12N7/00 , C12N2710/20022 , C12N2710/20023 , C12N2710/20051 , C12N2710/22022 , C12N2710/22023 , C12N2710/22051
摘要: The invention provides methods for the preparation of an isolated virus particle or virus-like particle by treating with an agent such that the particles are preferentially in the aqueous phase. The invention also provides methods of preparing a capsomere that is substantially-free of at least one host cell derived chaperone protein by treatment with an agent to selectively separate the capsomere from at least one chaperone protein.