公开(公告)号：EP1088285B1

公开(公告)日：2004-12-15

申请号：EP99912984.4

申请日：1999-03-30

申请人： The University of Adelaide ,  UNIVERSITY OF SOUTH AUSTRALIA ,  THE UNIVERSITY OF QUEENSLAND ,  The University of Melbourne ,  Compaq Computer Australia Pty Ltd ,  Telstra Corporation Limited ,  RLM Systems Pty Ltd ,  Flinders University ,  CEA Technologies Pty Limited ,  The Commonwealth of Australia Represented by DSTO

发明人： BAMFORD, Pascal ,  LOVELL, Brian

IPC分类号： G06T7/60 ,  G06F19/00 ,  G06K9/00 ,  G06K9/48

CPC分类号： G06K9/0014 ,  G06K9/6207 ,  G06T7/0012 ,  G06T7/12 ,  G06T7/143 ,  G06T7/149 ,  G06T2207/10056 ,  G06T2207/30012 ,  G06T2207/30024

公开(公告)号：EP1088285A1

公开(公告)日：2001-04-04

申请号：EP99912984.4

申请日：1999-03-30

申请人： Spire Technologies Pty Ltd. ,  The University of Adelaide ,  UNIVERSITY OF SOUTH AUSTRALIA ,  THE UNIVERSITY OF QUEENSLAND ,  The University of Melbourne ,  Compaq Computer Australia Pty Ltd ,  Telstra Corporation Limited ,  RLM Systems Pty Ltd ,  Flinders University ,  CEA Technologies Pty Limited ,  The Commonwealth of Australia Represented by DSTO

发明人： BAMFORD, Pascal ,  LOVELL, Brian

IPC分类号： G06T7/60 ,  G06F19/00

CPC分类号： G06K9/0014 ,  G06K9/6207 ,  G06T7/0012 ,  G06T7/12 ,  G06T7/143 ,  G06T7/149 ,  G06T2207/10056 ,  G06T2207/30012 ,  G06T2207/30024

摘要： A method of segmentation of cell nuclei is described that uses an active contours approach based on a Viterbi search algorithm. Also disclosed is an initialisation technique that maximises the probability of a correct segmentation. The invention also includes a method to classify cell nuclei according to the difficulty of correct segmentation. Nuclei that are difficult to segment can be rejected to minimise the probability of false positives. The probability of false positives can be driven close to 0 %.

摘要翻译： 描述了使用基于维特比搜索算法的主动轮廓方法的细胞核分割方法。 还公开了使正确分割的概率最大化的初始化技术。 本发明还包括根据正确分割的难度对细胞核进行分类的方法。 难以分裂的核可以被拒绝以最小化误报的可能性。 假阳性的概率可以接近0％。