公开(公告)号：EP4494702A3

公开(公告)日：2025-02-26

申请号：EP24196960.9

申请日：2015-06-24

Applicant: The University of Kansas

Inventor： BLAGG, Brian S. J. ,  DOBROWSKY, Rick T. ,  ANYIKA, Mercy

IPC: C07H15/203 ,  C07C233/05 ,  C07D309/10 ,  C07D311/08 ,  C07D307/20 ,  A61P25/00 ,  C07C233/18 ,  C07D311/16 ,  A61P3/10 ,  A61P9/00 ,  A61P9/10 ,  A61P13/12 ,  A61P25/02 ,  A61P27/02 ,  A61P29/00 ,  A61P35/00 ,  A61P25/28

Abstract: Provided herein are compounds of the formula:

wherein: n, X 1 , X 2 , R 1 , R 2 , R 3 , R 3 ', R 4 , R 4 ', R 5 , R 5 ', R 6 , and R 6 ' are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer.

公开(公告)号：EP4494702A2

公开(公告)日：2025-01-22

申请号：EP24196960.9

申请日：2015-06-24

Applicant: The University of Kansas

Inventor： BLAGG, Brian S. J. ,  DOBROWSKY, Rick T. ,  ANYIKA, Mercy

IPC: A61P25/00

Abstract: Provided herein are compounds of the formula:

wherein: n, X 1 , X 2 , R 1 , R 2 , R 3 , R 3 ', R 4 , R 4 ', R 5 , R 5 ', R 6 , and R 6 ' are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer.