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1.发明公开
公开(公告)号：EP3957996A1
公开(公告)日：2022-02-23
申请号：EP21183583.0
申请日：2016-10-05
IPC分类号： G01N33/543 , G01N33/542
摘要： Decoding methods are provided for identifying populations in assays, particularly multiplexing assays and those associated with fluidic devices.
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2.发明公开FLUIDIC DEVICES WITH FREEZE-THAW VALVES WITH ICE-NUCLEATING AGENTS AND RELATED METHODS OF OPERATION AND ANALYSIS 审中-公开具有冰核成分的带冻结阀的流体装置以及相关的操作和分析方法
公开(公告)号：EP3314183A1
公开(公告)日：2018-05-02
申请号：EP16748410.4
申请日：2016-07-22
IPC分类号： F26B5/10 , C12R1/38 , F16K99/00 , F16L55/103
摘要： Embodiments of the invention provide fluidic devices such as, but not limited to, microfluidic chips, with one or more freeze thaw valves (FTVs) employing one or more ice-nucleating agents (INAs), that can reliably operate to freeze at relatively higher temperatures and/or at faster rates than conventional microfluidic devices with FTV systems.
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公开(公告)号：EP2864764B1
公开(公告)日：2018-03-07
申请号：EP13806595.8
申请日：2013-06-05
IPC分类号： G01N27/447 , H01J49/16
CPC分类号： H01J49/165 , G01N27/4473 , G01N27/44743 , G01N27/44791 , G01N30/7266 , H01J49/0431 , H01J49/0445 , H01J49/26
摘要： Methods, systems and devices that generate differential axial transport in a fluidic device having at least one fluidic sample separation flow channel and at least one ESI emitter in communication with the at least one sample separation flow channel. In response to the generated differential axial transport, the at least one target analyte contained in a sample reservoir in communication with the sample separation channel is selectively transported to the at least one ESI emitter while inhibiting transport of contaminant materials contained in the sample reservoir toward the at least one ESI emitter thereby preferentially directing analyte molecules out of the at least one ESI emitter. The methods, systems and devices are particularly suitable for use with a mass spectrometer.
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公开(公告)号：EP3295160B1
公开(公告)日：2020-07-08
申请号：EP16724222.1
申请日：2016-05-10
IPC分类号： G01N27/447 , G01N30/72
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公开(公告)号：EP3588098A1
公开(公告)日：2020-01-01
申请号：EP19191859.8
申请日：2014-02-26
IPC分类号： G01N35/08 , G01N27/02 , G01N33/487 , G01N33/483 , B01L3/00 , G01N27/447
摘要： Devices for controlling the capture, trapping, and transport of macromolecules include at least one fluidic transport nanochannel that intersects and is in fluid communication with at least one transverse nanochannel with (shallow) regions and/or with integrated transverse electrodes that enable fine control of molecule transport dynamics and facilitates analyses of interest, e.g., molecular identification, length determination, localized (probe) mapping and the like.
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公开(公告)号：EP4357022A3
公开(公告)日：2024-07-10
申请号：EP24162498.0
申请日：2019-11-05
IPC分类号： B01L3/00
CPC分类号： B01L2200/062120130101 , B01L3/502761 , B01L2300/081620130101 , B01L3/5085 , B01L3/502715 , B01L2200/066820130101 , B01L2300/086420130101 , B01L2300/1820130101 , B01L2400/048720130101 , B01L2400/04320130101
摘要： Analysis systems with a housing having a chamber sized and configured to receive at least one microfluidic device. The systems also include an optic system coupled to the housing in optical communication with the at least one microfluidic device, a controller coupled to the optic system, a heat source coupled to the optic system and thermally coupled to the at least one microfluidic device held in the housing, and a sub-array selection module in communication with the controller. The sub-array selection module is configured to select a sub-set of sets of microwells of at least one fluid channel of the microfluidic device for imaging by the optic system after a reaction step (e.g., one thermocycle) during an assay.
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公开(公告)号：EP3857228A2
公开(公告)日：2021-08-04
申请号：EP19898938.6
申请日：2019-09-24
IPC分类号： G01N33/543 , G01N33/58 , C12Q1/6806
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9.发明公开
公开(公告)号：EP3329279A2
公开(公告)日：2018-06-06
申请号：EP16858484.5
申请日：2016-10-05
IPC分类号： G01N33/542 , G01N33/543
CPC分类号： G01N33/542 , G01N33/54313
摘要： Decoding methods are provided for identifying populations in assays, particularly multiplexing assays and those associated with fluidic devices.
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10.发明公开INTEGRATED SAMPLE PROCESSING FOR ELECTROSPRAY IONIZATION DEVICES 有权INTEGRIERTE PROBENVERARBEITUNGFÜRELEKTROSPRAY-IONISIERUNGSVORRICHTUNGEN
公开(公告)号：EP2864764A1
公开(公告)日：2015-04-29
申请号：EP13806595.8
申请日：2013-06-05
IPC分类号： G01N21/75
CPC分类号： H01J49/165 , G01N27/4473 , G01N27/44743 , G01N27/44791 , G01N30/7266 , H01J49/0431 , H01J49/0445 , H01J49/26
摘要： Methods, systems and devices that generate differential axial transport in a fluidic device having at least one fluidic sample separation flow channel and at least one ESI emitter in communication with the at least one sample separation flow channel. In response to the generated differential axial transport, the at least one target analyte contained in a sample reservoir in communication with the sample separation channel is selectively transported to the at least one ESI emitter while inhibiting transport of contaminant materials contained in the sample reservoir toward the at least one ESI emitter thereby preferentially directing analyte molecules out of the at least one ESI emitter. The methods, systems and devices are particularly suitable for use with a mass spectrometer.
摘要翻译： 在具有至少一个流体样品分离流动通道的流体装置中产生差分轴向输送的方法，系统和装置以及与至少一个样品分离流动通道连通的至少一个ESI发射器。 响应于产生的差分轴向传输，包含在与样品分离通道连通的样品储存器中的至少一个目标分析物被选择性地输送到至少一个ESI发射体，同时抑制样品储存器中包含的污染物质向着 至少一个ESI发射体从而优先地将分析物分子导出至少一个ESI发射体。 方法，系统和装置特别适用于质谱仪。
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