专利检索 ap:("TheVax Genetics Vaccine Co., Ltd.") AND inv:"LIN, Yin-Ching" 第 1 页

1.

发明公开
A VACCINE COMPOSITION COMPRISING AN IMMUNOGENIC PROTEIN AND COMBINATION ADJUVANTS FOR USE IN ELICITING ANTIGEN-SPECIFIC T-CELL RESPONSES 审中-公开
标题翻译：包含免疫原性蛋白和组合佐剂的疫苗组合物用于诱导抗原特异性T细胞应答

公开(公告)号：EP3261667A1

公开(公告)日：2018-01-03

申请号：EP16756299.0

申请日：2016-02-24

申请人： TheVax Genetics Vaccine Co., Ltd.

发明人： WU, Chia-Mao , WU, Jiun-Ming , CHIU, Yi-Tsui , LIN, Yin-Ching , CHUANG, Hsien-Kai , HSIEH, Fu-Tan , CHEN, Kuan-Ming

IPC分类号： A61K39/21 , A61K47/50

CPC分类号： A61K39/39 , A61K38/164 , A61K38/1774 , A61K39/12 , A61K2039/545 , A61K2039/55511 , A61K2039/55561 , A61K2039/55572 , A61K2039/55577 , A61K2039/585 , A61K2039/6031 , A61K2039/6037 , C12N7/00 , C12N2710/20033 , C12N2710/20034 , C12N2710/20071 , Y02A50/386

摘要： Vaccine compositions for use in inducing enhanced antigen-specific T cell-mediated immune responses in a subject in need thereof are disclosed. The composition comprises (a) a therapeutically effective amount of an immunogenic protein comprising at least an antigen of a pathogen; (b) a saponin-base adjuvant selected from the group consisting of GPI-0100, Quil A, QS-21; and (c) a Toll-like receptor (TLR) agonist adjuvant selected from the group consisting of monophosphoryl lipid A (MPL), and CpG1826.