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1.发明授权1-(2-PHENOXYMETHYLHETEROARYL)PIPERIDINE AND PIPERAZINE COMPOUNDS 有权1-（2- PHENOXYMETHYLHETEROARYL）哌啶和哌嗪化合物
公开(公告)号：EP2550252B1
公开(公告)日：2015-05-06
申请号：EP11714878.3
申请日：2011-03-21
IPC分类号： C07D213/30 , C07D213/61 , C07D213/74 , C07D307/42 , C07D307/56 , C07D333/16 , A61K31/4427 , A61K31/341 , A61K31/381 , A61P29/00
CPC分类号： C07D401/04 , C07D213/30 , C07D213/61 , C07D213/74 , C07D307/42 , C07D307/56 , C07D333/16 , C07D405/04 , C07D409/04
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公开(公告)号：EP2454234B1
公开(公告)日：2018-04-11
申请号：EP10732609.2
申请日：2010-07-12
发明人： STANGELAND, Eric L. , SAITO, Daisuke Roland , HUGHES, Adam , SCHMIDT, Jane , VAN DYKE, Priscilla , PATTERSON, Lori Jean
IPC分类号： C07D207/08 , A61P25/00 , A61K31/40 , A61P29/00
CPC分类号： C07D207/08 , A61K31/40 , A61K45/06
摘要： In one aspect, the invention relates to compounds of formula I: where R1-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
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公开(公告)号：EP2635571B1
公开(公告)日：2015-08-12
申请号：EP11784875.4
申请日：2011-11-03
发明人： MCKINNELL, Robert Murray , LONG, Daniel D. , VAN ORDEN, Lori Jean , JIANG, Lan , LOO, Mandy , SAITO, Daisuke Roland , ZIPFEL, Sheila , STANGELAND, Eric L. , LEPACK, Kassandra , OGAWA, Gavin , HUANG, Xiaojun , ZHANG, Weijiang
IPC分类号： C07D403/14 , A61K31/4025 , A61K31/12
CPC分类号： C07D401/14 , A61K31/496 , A61K45/06 , C07D403/14
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公开(公告)号：EP2627630B1
公开(公告)日：2014-12-31
申请号：EP11773367.5
申请日：2011-10-10
IPC分类号： C07D207/08 , C07D401/12 , A61K31/40 , A61P11/00
CPC分类号： C07D207/08 , C07D207/12 , C07D401/12
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