摘要:
The device comprises a blood vessel engaging portion which is initially disposable in a radially collapsed configuration such that the device may be passed into the lumen of the tapered segment of the blood vessel, and subsequently expandable to an operative configuration where it will frictionally engage the surrounding blood vessel wall to hold the device in fixed position within the blood vessel lumen. It also has a lumen blocking portion which is affixed to the engaging portion. The lumen blocking portion is configured such that, when the engaging portion is in its operative configuration and in contact with the blood vessel wall, the lumen blocking portion will block the flow of blood in at least one direction through the lumen. The blood vessel engaging portion is a wire frame.
摘要:
Apparatus (10) for creating channels between adjacent blood vessels include a cutting element (22) fixed on a catheter (12) for creating a channel in a wall of a blood vessel. A clip (34) engages tissue thereunder for maintaining the cutting element (22) in contact with tissue being cut. Orientation markers (32, 33) may facilitate rotationally orienting the cutting element (22). The catheter (12) is advanced into a blood vessel, and a distal portion (24) of the catheter (12) is directed through a wall of the vessel towards an adjacent vessel until the cutting element (22) is in contact with tissue therebetween. The catheter (12) is directed axially along the vessel, thereby creating a channel in the tissue using the cutting element (22). In another embodiment, the apparatus (310) may include first and second elongated elements (326a, 326b) pivotably coupled to one another having an aperture-creating assembly (322) disposed between them.
摘要:
A system of catheter devices (10), and methods for forming channels or passageways between a luminal anatomical structure (e.g., a blood vessel), a target location (e.g., another blood vessel, an organ, a mass of tissue, etc.) for the purpose of rerouting blood flow or for delivering a substance or instrument, etc. to the target location.
摘要:
This invention is methods, devices, and systems for re-vascularization, and/or performing other medical procedures at a vascular or non-vascular intra-corporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway from a blood vessel to a vascular or non-vascular target location. In the re-vascularization methods the extravascular passageway is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices (100, 103) and systems (138) which are usable to form the extravascular passageways of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.
摘要:
This invention is methods and apparatus for connecting two anatomical passageways, such as blood vessels, in side-to-side fashion. Openings are formed in the sidewalls of the passageways, and a connector apparatus (10) of the present invention is implanted within such openings, and extends between the passageways or blood vessels (BV1, BV2) so as to connect the passageways or blood vessels (BV1, BV2) such that the openings are held in direct alignment with one another, thereby allowing body fluids to pass from one passageway into the other.
摘要:
This invention is methods, devices, and systems for re-vascularization, and/or performing other medical procedures at a vascular or non-vascular intra-corporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway from a blood vessel to a vascular or non-vascular target location. In the re-vascularization methods the extravascular passageway is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices (100, 103) and systems (138) which are usable to form the extravascular passageways of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.
摘要:
A trans-vascular system (10) for delivering a drug to a tissue region from a blood vessel, such as a coronary vein, includes a catheter (12) having a distal portion (26) with puncturing (14), orientation (16), drug delivery (62), and imaging elements (18). The puncturing element (14) is deployed for penetrating the vessel wall to access the tissue region. The orientation element (16), e.g., a 'cage' including a plurality of struts (38, 40), and/or a radiopaque marker has a predetermined relationship with the location of the orientation element (16) with respect to the tissue region to orient the puncturing element (14). The catheter (12) is percutaneously introducing into the vessel, the puncturing element (14) is oriented towards the tissue region, the puncturing element (14) is deployed to access the tissue region, and the drug is delivered to the tissue region. An ablation device (230) may also be deployed to create a cavity in the tissue region for receiving the drug therein, or an indwelling catheter (214) may be advanced into, and left in the tissue region. An implanted reservoir device (350) is also disclosed, including an enclosed membrane (354) on an expandable frame (352) that defines a reservoir, and includes a porous region. The reservoir device may be deployed, expanded within a blood vessel, and may be filled in situ or pre-filled with a drug that passes through the porous region. Alternatively, a pair of expandable endovascular blockers may be used to isolate a section of a blood vessel which may be filled with a drug that may be absorbed by the surrounding tissue.