公开(公告)号：EP1067869B1

公开(公告)日：2005-11-02

申请号：EP99916238.1

申请日：1999-03-31

申请人： Transvascular, Inc.

发明人： FLAHERTY, J., Christopher ,  WHITT, Jason, B. ,  CHANG, John, Y. ,  THOLFSEN, David, R. ,  EVARD, Phillip, C.

IPC分类号： A61B17/22

CPC分类号： A61M25/0108 ,  A61B17/22 ,  A61B17/3207 ,  A61B2017/00252 ,  A61B2017/00455 ,  A61B2017/22077 ,  A61B2090/3784 ,  A61B2090/3925

摘要： A catheter device (11) that is useable to penetrate from a blood vessel in which the catheter device (11) is positioned to a target location, comprises a flexible catheter advanced into the blood vessel, a tissue penetrator (85) which is useable to penetrate from the blood vessel to the target location when properly aimed. Further said catheter includes an imaging transducer (81) fixedly mounted on or within the catheter body (13) to provide an imaging signal from which an image of the target location can be obtained. The catheter device (11) may include an imaged marker (101) on the catheter to form on the image obtainable from the imaging signal a penetrator path indication that indicates the path that will be followed by the tissue penetrator when the tissue penetrator (85) exits from the catheter (11). Alternatively, or in addition thereto, the imaging transducer (81) may comprise a plurality of imaging elements.

公开(公告)号：EP0879068A1

公开(公告)日：1998-11-25

申请号：EP97904084.0

申请日：1997-01-31

申请人： Transvascular, Inc.

发明人： EVARD, Philip, C. ,  FLAHERTY, J., C. ,  GARIBOTTO, John, T. ,  MACAULAY, Patrick, E. ,  MACHOLD, Timothy, R. ,  MAKOWER, Joshua ,  WHITT, Jason, B. ,  JENSEN, Marc

IPC分类号： A61B1 ,  A61B17 ,  A61B18 ,  A61B19 ,  A61F2 ,  A61M25

CPC分类号： A61B1/3137 ,  A61B17/00234 ,  A61B17/00491 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/12022 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12131 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B17/12186 ,  A61B17/1219 ,  A61B17/3417 ,  A61B17/3496 ,  A61B18/00 ,  A61B18/1445 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/24 ,  A61B90/361 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/00504 ,  A61B2017/0641 ,  A61B2017/0647 ,  A61B2017/0649 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/1205 ,  A61B2017/12127 ,  A61B2017/22038 ,  A61B2017/22077 ,  A61B2017/306 ,  A61B2017/347 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2018/00404 ,  A61B2018/00869 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/378 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3958 ,  A61F2/07 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/95 ,  A61F2002/075 ,  A61F2002/30079 ,  A61F2002/8486 ,  A61F2210/009 ,  A61M2025/0076 ,  A61M2025/0096 ,  A61M2025/1052

摘要： The device comprises a blood vessel engaging portion which is initially disposable in a radially collapsed configuration such that the device may be passed into the lumen of the tapered segment of the blood vessel, and subsequently expandable to an operative configuration where it will frictionally engage the surrounding blood vessel wall to hold the device in fixed position within the blood vessel lumen. It also has a lumen blocking portion which is affixed to the engaging portion. The lumen blocking portion is configured such that, when the engaging portion is in its operative configuration and in contact with the blood vessel wall, the lumen blocking portion will block the flow of blood in at least one direction through the lumen. The blood vessel engaging portion is a wire frame.

摘要翻译： 该装置包括血管接合部分，其最初是一次性处于径向收缩的构造，使得该装置可以进入血管的锥形部分的内腔中，并且随后可扩展到其将摩擦地接合周围 血管壁将装置保持在血管腔内的固定位置。 它还具有固定到接合部分的管腔阻塞部分。 管腔阻塞部分构造成使得当接合部分处于其操作构造并与血管壁接触时，管腔阻塞部分将阻止至少一个方向上的血液流过该内腔。 血管接合部是线框。

公开(公告)号：EP0954248B1

公开(公告)日：2004-09-15

申请号：EP96936499.1

申请日：1996-10-11

申请人： Transvascular, Inc.

发明人： EVARD, Philip, C. ,  FLAHERTY, J., C. ,  GARIBOTTO, John, T. ,  MACAULAY, Patrick, E. ,  MACHOLD, Timothy, R. ,  MAKOWER, Joshua ,  WHITT, Jason, B. ,  VIDAL, Clade, A. ,  REDMOND, Russel, J. ,  BANKS, Thomas

IPC分类号： A61B19/00 ,  A61B17/34 ,  A61B17/11

CPC分类号： A61B1/3137 ,  A61B17/00234 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/12022 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12131 ,  A61B17/12136 ,  A61B17/320725 ,  A61B17/3417 ,  A61B17/3496 ,  A61B18/00 ,  A61B18/1445 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/24 ,  A61B90/361 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/003 ,  A61B2017/00331 ,  A61B2017/00504 ,  A61B2017/00637 ,  A61B2017/00668 ,  A61B2017/0641 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/12127 ,  A61B2017/22038 ,  A61B2017/22077 ,  A61B2017/22095 ,  A61B2017/306 ,  A61B2017/347 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2018/00404 ,  A61B2018/00869 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/378 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3958 ,  A61F2/07 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/95 ,  A61F2002/30079 ,  A61F2002/8486 ,  A61F2210/009 ,  A61M2025/0076 ,  A61M2025/0096 ,  A61M2025/018 ,  A61M2025/1052

摘要： This invention is methods, devices, and systems for re-vascularization, and/or performing other medical procedures at a vascular or non-vascular intra-corporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway from a blood vessel to a vascular or non-vascular target location. In the re-vascularization methods the extravascular passageway is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices (100, 103) and systems (138) which are usable to form the extravascular passageways of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.

公开(公告)号：EP1066070A1

公开(公告)日：2001-01-10

申请号：EP99909978.1

申请日：1999-03-17

申请人： Transvascular, Inc.

发明人： FLAHERTY, J., Christopher ,  MAKOWER, Joshua ,  EVARD, Philip, C. ,  MACAULAY, Patrick, E. ,  WHITT, Jason, B. ,  COLLOTON, Robert, C. ,  MACFARLANE, K., Angela

IPC分类号： A61M5/00 ,  A61M5/178

CPC分类号： A61M25/0084 ,  A61B8/12 ,  A61B17/00491 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/12022 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12172 ,  A61B17/22 ,  A61B17/3417 ,  A61B18/00 ,  A61B18/1477 ,  A61B18/1492 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/00504 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/12127 ,  A61B2017/22077 ,  A61B2017/306 ,  A61B2017/347 ,  A61B2018/00392 ,  A61B2018/1425 ,  A61F2/2493 ,  A61F2002/30079 ,  A61F2210/009 ,  A61M5/007 ,  A61M5/46 ,  A61M25/0068 ,  A61M25/0069 ,  A61M25/007 ,  A61M25/0108 ,  A61M39/0208 ,  A61M39/04 ,  A61M2025/0037 ,  A61M2025/0076 ,  A61M2025/0086 ,  A61M2025/0087 ,  A61M2025/009 ,  A61M2025/0096 ,  A61M2025/1052

摘要： A trans-vascular system (10) for delivering a drug to a tissue region from a blood vessel, such as a coronary vein, includes a catheter (12) having a distal portion (26) with puncturing (14), orientation (16), drug delivery (62), and imaging elements (18). The puncturing element (14) is deployed for penetrating the vessel wall to access the tissue region. The orientation element (16), e.g., a 'cage' including a plurality of struts (38, 40), and/or a radiopaque marker has a predetermined relationship with the location of the orientation element (16) with respect to the tissue region to orient the puncturing element (14). The catheter (12) is percutaneously introducing into the vessel, the puncturing element (14) is oriented towards the tissue region, the puncturing element (14) is deployed to access the tissue region, and the drug is delivered to the tissue region. An ablation device (230) may also be deployed to create a cavity in the tissue region for receiving the drug therein, or an indwelling catheter (214) may be advanced into, and left in the tissue region. An implanted reservoir device (350) is also disclosed, including an enclosed membrane (354) on an expandable frame (352) that defines a reservoir, and includes a porous region. The reservoir device may be deployed, expanded within a blood vessel, and may be filled in situ or pre-filled with a drug that passes through the porous region. Alternatively, a pair of expandable endovascular blockers may be used to isolate a section of a blood vessel which may be filled with a drug that may be absorbed by the surrounding tissue.

公开(公告)号：EP1067874A1

公开(公告)日：2001-01-17

申请号：EP99917329.7

申请日：1999-03-31

申请人： Transvascular, Inc.

发明人： FLAHERTY, J., Christopher ,  WHITT, Jason, B. ,  MACAULAY, Patrick, E. ,  THOLFSEN, David, R. ,  GARIBOTTO, John, T. ,  EVARD, Phillip, C.

IPC分类号： A61B17/22

CPC分类号： A61M25/0108 ,  A61B17/22 ,  A61B17/3207 ,  A61B2017/00252 ,  A61B2017/00455 ,  A61B2017/22077 ,  A61B2090/3784 ,  A61B2090/3925

摘要： A system of catheter devices (10), and methods for forming channels or passageways between a luminal anatomical structure (e.g., a blood vessel), a target location (e.g., another blood vessel, an organ, a mass of tissue, etc.) for the purpose of rerouting blood flow or for delivering a substance or instrument, etc. to the target location.

公开(公告)号：EP1067869A2

公开(公告)日：2001-01-17

申请号：EP99916238.1

申请日：1999-03-31

申请人： Transvascular, Inc.

发明人： FLAHERTY, J., Christopher ,  WHITT, Jason, B. ,  CHANG, John, Y. ,  THOLFSEN, David, R. ,  EVARD, Phillip, C.

IPC分类号： A61B8/00

CPC分类号： A61M25/0108 ,  A61B17/22 ,  A61B17/3207 ,  A61B2017/00252 ,  A61B2017/00455 ,  A61B2017/22077 ,  A61B2090/3784 ,  A61B2090/3925

摘要： A catheter device (11) that is useable to penetrate from a blood vessel in which the catheter device (11) is positioned to a target location, comprises a flexible catheter advanced into the blood vessel, a tissue penetrator (85) which is useable to penetrate from the blood vessel to the target location when properly aimed. Further said catheter includes an imaging transducer (81) fixedly mounted on or within the catheter body (13) to provide an imaging signal from which an image of the target location can be obtained. The catheter device (11) may include an imaged marker (101) on the catheter to form on the image obtainable from the imaging signal a penetrator path indication that indicates the path that will be followed by the tissue penetrator when the tissue penetrator (85) exits from the catheter (11). Alternatively, or in addition thereto, the imaging transducer (81) may comprise a plurality of imaging elements.

公开(公告)号：EP0954248A1

公开(公告)日：1999-11-10

申请号：EP96936499.0

申请日：1996-10-11

申请人： Transvascular, Inc.

发明人： EVARD, Philip, C. ,  FLAHERTY, J., C. ,  GARIBOTTO, John, T. ,  MACAULAY, Patrick, E. ,  MACHOLD, Timothy, R. ,  MAKOWER, Joshua ,  WHITT, Jason, B. ,  VIDAL, Clade, A. ,  REDMOND, Russel, J. ,  BANKS, Thomas

IPC分类号： A61B ,  A61B17 ,  A61B1 ,  A61B18 ,  A61F2 ,  A61B19 ,  A61M25

CPC分类号： A61B1/3137 ,  A61B17/00234 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/12022 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12131 ,  A61B17/12136 ,  A61B17/320725 ,  A61B17/3417 ,  A61B17/3496 ,  A61B18/00 ,  A61B18/1445 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/24 ,  A61B90/361 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/003 ,  A61B2017/00331 ,  A61B2017/00504 ,  A61B2017/00637 ,  A61B2017/00668 ,  A61B2017/0641 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/12127 ,  A61B2017/22038 ,  A61B2017/22077 ,  A61B2017/22095 ,  A61B2017/306 ,  A61B2017/347 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2018/00404 ,  A61B2018/00869 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/378 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3958 ,  A61F2/07 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/95 ,  A61F2002/30079 ,  A61F2002/8486 ,  A61F2210/009 ,  A61M2025/0076 ,  A61M2025/0096 ,  A61M2025/018 ,  A61M2025/1052

摘要： This invention is methods, devices, and systems for re-vascularization, and/or performing other medical procedures at a vascular or non-vascular intra-corporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway from a blood vessel to a vascular or non-vascular target location. In the re-vascularization methods the extravascular passageway is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices (100, 103) and systems (138) which are usable to form the extravascular passageways of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.

公开(公告)号：EP0932426A1

公开(公告)日：1999-08-04

申请号：EP97904086.0

申请日：1997-01-31

申请人： Transvascular, Inc.

发明人： EVARD, Philip, C. ,  FLAHERTY, J., C. ,  GARIBOTTO, John, T. ,  MACAULAY, Patrick, E. ,  MACHOLD, Timothy, R. ,  MAKOWER, Joshua ,  WHITT, Jason, B. ,  ROTH, Alex, T.

IPC分类号： A61B1 ,  A61B17 ,  A61B18 ,  A61B19 ,  A61F2 ,  A61M25

CPC分类号： A61B1/3137 ,  A61B17/00234 ,  A61B17/00491 ,  A61B17/0643 ,  A61B17/11 ,  A61B18/00 ,  A61B18/1445 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/24 ,  A61B90/361 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/00504 ,  A61B2017/0641 ,  A61B2017/0647 ,  A61B2017/0649 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/22038 ,  A61B2017/22077 ,  A61B2018/00392 ,  A61B2018/00404 ,  A61B2018/00869 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/378 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3958 ,  A61F2/07 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/30079 ,  A61F2002/8486 ,  A61F2210/009 ,  A61F2230/001 ,  A61M2025/0076 ,  A61M2025/0096 ,  A61M2025/1052

摘要： This invention is methods and apparatus for connecting two anatomical passageways, such as blood vessels, in side-to-side fashion. Openings are formed in the sidewalls of the passageways, and a connector apparatus (10) of the present invention is implanted within such openings, and extends between the passageways or blood vessels (BV1, BV2) so as to connect the passageways or blood vessels (BV1, BV2) such that the openings are held in direct alignment with one another, thereby allowing body fluids to pass from one passageway into the other.