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公开(公告)号:EP1294691B1
公开(公告)日:2006-11-08
申请号:EP01938399.1
申请日:2001-06-12
申请人: Tularik Limited
发明人: LIVELY, Sarah Elizabeth , WASZKOWYCZ, Bohdan , HARRISON, Martin James , FARTHING, Christopher Neil , JOHNSON, Keith Michael
IPC分类号: C07D211/34 , A61P7/02 , A61K31/428 , A61K31/166 , A61K31/445 , C07D277/46 , A61K31/425 , C07D277/40 , C07D213/56 , C07D233/54 , C07D273/00 , C07D307/54 , C07D333/60 , C07D277/30 , C07D401/12 , C07D213/73 , C07D213/61 , C07D209/08 , C07D307/79
CPC分类号: C07C237/42 , C07B2200/07 , C07C2601/14 , C07C2602/08 , C07D209/08 , C07D211/34 , C07D211/46 , C07D211/60 , C07D213/56 , C07D213/61 , C07D213/73 , C07D233/64 , C07D273/00 , C07D277/30 , C07D277/40 , C07D277/46 , C07D277/52 , C07D277/68 , C07D277/82 , C07D307/54 , C07D307/79 , C07D333/36 , C07D333/60 , C07D401/12 , C07D417/12
摘要: Compounds of formula (I) where R5, R6a, each X, L, Cy and Lp are as defined in the specification, are tryptase inhibitors useful as antiinflammatory agents.
摘要翻译: 其中R5,R6a,X,L,Cy和Lp如说明书中所定义的式(I)化合物是用作抗炎剂的类胰蛋白酶抑制剂。
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公开(公告)号:EP1294691A1
公开(公告)日:2003-03-26
申请号:EP01938399.1
申请日:2001-06-12
申请人: Tularik Limited
发明人: LIVELY, Sarah Elizabeth , WASZKOWYCZ, Bohdan , HARRISON, Martin James , FARTHING, Christopher Neil , JOHNSON, Keith Michael
IPC分类号: C07D211/34 , A61P7/02 , A61K31/428 , A61K31/166 , A61K31/445 , C07D277/46 , A61K31/425 , C07D277/40 , C07D213/56 , C07D233/54 , C07D273/00 , C07D307/54 , C07D333/60 , C07D277/30 , C07D401/12 , C07D213/73 , C07D213/61 , C07D209/08 , C07D307/79
CPC分类号: C07C237/42 , C07B2200/07 , C07C2601/14 , C07C2602/08 , C07D209/08 , C07D211/34 , C07D211/46 , C07D211/60 , C07D213/56 , C07D213/61 , C07D213/73 , C07D233/64 , C07D273/00 , C07D277/30 , C07D277/40 , C07D277/46 , C07D277/52 , C07D277/68 , C07D277/82 , C07D307/54 , C07D307/79 , C07D333/36 , C07D333/60 , C07D401/12 , C07D417/12
摘要: Compounds of formula (I) where R5, R6a, each X, L, Cy and Lp are as defined in the specification, are tryptase inhibitors useful as antiinflammatory agents.
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公开(公告)号:EP1240154B1
公开(公告)日:2007-02-28
申请号:EP00981478.1
申请日:2000-12-13
申请人: Tularik Limited
发明人: LIVELY, Sarah Elizabeth , WASZKOWYCZ, Bohdan , HARRISON, Martin James , FARTHING, Christopher Neil , JOHNSON, Keith Michael
IPC分类号: C07D333/36 , A61K31/428 , C07D277/82 , C07D215/38 , C07D295/12 , C07D209/08 , C07D295/18 , C07D211/60 , C07D217/06 , C07C237/36 , C07D211/46 , C07D403/06 , C07D401/06 , C07D417/06 , C07D295/14
CPC分类号: C07D217/04 , C07B2200/07 , C07C237/36 , C07C237/42 , C07C255/60 , C07C2601/14 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07D209/08 , C07D209/30 , C07D209/34 , C07D209/42 , C07D211/26 , C07D211/34 , C07D211/46 , C07D211/60 , C07D213/53 , C07D213/56 , C07D213/61 , C07D213/73 , C07D213/74 , C07D213/82 , C07D215/38 , C07D217/06 , C07D231/56 , C07D233/64 , C07D235/06 , C07D241/24 , C07D273/00 , C07D277/28 , C07D277/30 , C07D277/40 , C07D277/46 , C07D277/52 , C07D277/64 , C07D277/68 , C07D277/82 , C07D295/135 , C07D295/185 , C07D307/54 , C07D307/79 , C07D317/68 , C07D333/36 , C07D333/38 , C07D333/60 , C07D333/68 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D405/14 , C07D413/14 , C07D417/06 , C07D417/12 , C07D487/04
摘要: Compounds of formula (I) where R5, R6a, each X, L, Cy and Lp are as defined in the specification, are tryptase inhibitors useful as antiinflammatory agents.
摘要翻译: 式(I)的化合物,其中R 5,R 6a,各X,L,Cy和Lp如说明书中所定义,是用作抗炎剂的类胰蛋白酶抑制剂。
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公开(公告)号:EP1240154A1
公开(公告)日:2002-09-18
申请号:EP00981478.1
申请日:2000-12-13
申请人: Tularik Limited
发明人: LIVELY, Sarah Elizabeth , WASZKOWYCZ, Bohdan , HARRISON, Martin James , FARTHING, Christopher Neil , JOHNSON, Keith Michael
IPC分类号: C07D333/36 , A61K31/428 , C07D277/82 , C07D215/38 , C07D295/12 , C07D209/08 , C07D295/18 , C07D211/60 , C07D217/06 , C07C237/36 , C07D211/46 , C07D403/06 , C07D401/06 , C07D417/06 , C07D295/14
CPC分类号: C07D217/04 , C07B2200/07 , C07C237/36 , C07C237/42 , C07C255/60 , C07C2601/14 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07D209/08 , C07D209/30 , C07D209/34 , C07D209/42 , C07D211/26 , C07D211/34 , C07D211/46 , C07D211/60 , C07D213/53 , C07D213/56 , C07D213/61 , C07D213/73 , C07D213/74 , C07D213/82 , C07D215/38 , C07D217/06 , C07D231/56 , C07D233/64 , C07D235/06 , C07D241/24 , C07D273/00 , C07D277/28 , C07D277/30 , C07D277/40 , C07D277/46 , C07D277/52 , C07D277/64 , C07D277/68 , C07D277/82 , C07D295/135 , C07D295/185 , C07D307/54 , C07D307/79 , C07D317/68 , C07D333/36 , C07D333/38 , C07D333/60 , C07D333/68 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D405/14 , C07D413/14 , C07D417/06 , C07D417/12 , C07D487/04
摘要: Compounds of formula (I) where R5, R6a, each X, L, Cy and Lp are as defined in the specification, are tryptase inhibitors useful as antiinflammatory agents.
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