专利检索 ap:("UCB Pharma, S.A.") AND inv:"OWENS, Andrew, Pate" 第 1 页

1.

发明公开
QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS 有权
标题翻译：喹啉和喹喔啉作为激酶抑制剂

公开(公告)号：EP2499129A1

公开(公告)日：2012-09-19

申请号：EP10781864.3

申请日：2010-11-11

申请人： UCB Pharma, S.A.

发明人： ALLEN, Daniel, Rees , BÜRLI, Roland , HAUGHAN, Alan, Findlay , MATTEUCCI, Mizio , OWENS, Andrew, Pate , RAPHY, Gilles , SHARPE, Andrew

IPC分类号： C07D403/04 , C07D487/04 , A61K31/517 , A61P29/00 , A61P25/28 , A61P35/00 , A61P9/00

CPC分类号： C07D403/04 , C07D487/04

摘要： A series of quinoline and quinoxaline derivatives, substituted by an optionally substituted bicyclic heteroaryl moiety consisting of two fused six-membered aromatic rings attached via an alkylene chain optionally linked to a heteroatom, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

2.

发明授权
QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS 有权
标题翻译：喹啉和喹喔啉作为激酶抑制剂

公开(公告)号：EP2499129B1

公开(公告)日：2014-07-30

申请号：EP10781864.3

申请日：2010-11-11

申请人： UCB Pharma, S.A.

发明人： ALLEN, Daniel, Rees , BÜRLI, Roland , HAUGHAN, Alan, Findlay , MATTEUCCI, Mizio , OWENS, Andrew, Pate , RAPHY, Gilles , SHARPE, Andrew

IPC分类号： C07D403/04 , C07D487/04 , A61K31/517 , A61P29/00 , A61P25/28 , A61P35/00 , A61P9/00

CPC分类号： C07D403/04 , C07D487/04

3.

发明公开
QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS 有权
标题翻译：喹啉和喹喔啉作为激酶抑制剂

公开(公告)号：EP2499144A1

公开(公告)日：2012-09-19

申请号：EP10784275.9

申请日：2010-11-11

申请人： UCB Pharma, S.A.

发明人： BÜRLI, Roland , HAUGHAN, Alan, Findlay , MATTEUCCI, Mizio , OWENS, Andrew, Pate , RAPHY, Gilles , SHARPE, Andrew

IPC分类号： C07D487/04 , C07D495/04 , A61K31/522 , A61P29/00 , A61P31/00 , A61P37/00 , A61P9/02 , A61P25/28 , A61P3/00 , A61P35/00 , A61P25/00 , A61P27/02

CPC分类号： C07D487/04 , C07D495/04

摘要： A series of quinoline and quinoxaline derivatives, substituted by a fused bicyclic pyridine or pyrimidine moiety attached via an alkylene chain optionally linked to a heteroatom, being selective inhibitors of P13 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

4.

发明公开
TRIAZINE DERIVATIVES AS KINASE INHIBITORS 有权
标题翻译：三嗪衍生物作为激酶抑制剂的

公开(公告)号：EP2403847A1

公开(公告)日：2012-01-11

申请号：EP10706035.2

申请日：2010-03-02

申请人： UCB Pharma, S.A.

发明人： ALLEN, Daniel, Rees , BÜRLI, Roland , HAUGHAN, Alan, Findlay , MACDONALD, Jonathan, David , MATTEUCCI, Mizio , NASH, David, John , OWENS, Andrew, Pate , RAPHY, Gilles , SAVILLE-STONES, Elizabeth, Anne , SHARPE, Andrew

IPC分类号： C07D401/14 , A61K31/47 , A61P9/00

CPC分类号： A61K31/47 , C07D401/14

摘要： A series of substituted [1,3,5]triazin-2-yl derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

5.

发明公开
FUSED PYRIDINE AND PYRAZINE DERIVATIVES AS KINASE INHIBITORS 有权
标题翻译： CHINOLIN-DERIVATE ALS PI3K-KINASE-INHIBITOREN

公开(公告)号：EP2396315A1

公开(公告)日：2011-12-21

申请号：EP10703498.5

申请日：2010-02-11

申请人： UCB Pharma, S.A.

发明人： ALLEN, Daniel, Rees , BROWN, Julien, Alistair , BÜRLI, Roland , HAUGHAN, Alan, Findlay , MACDONALD, Jonathan, David , MATTEUCCI, Mizio , OWENS, Andrew, Pate , RAPHY, Gilles , SAVILLE-STONES, Elizabeth, Anne , SHARPE, Andrew

IPC分类号： C07D401/12 , C07D401/14 , C07D471/04 , C07D487/04 , C07D495/04 , A61K31/4709 , A61K31/52 , A61P29/00 , A61P37/00

CPC分类号： C07D401/12 , C07D401/14 , C07D471/04 , C07D487/04 , C07D495/04

摘要： A series of amino-substituted fused pyridine and pyrazine derivatives, in particular amino-substituted quinoline and quinoxaline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

6.

发明授权
QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS 有权
标题翻译：喹啉和喹喔啉作为激酶抑制剂

公开(公告)号：EP2499144B1

公开(公告)日：2013-10-23

申请号：EP10784275.9

申请日：2010-11-11

申请人： UCB Pharma, S.A.

发明人： BÜRLI, Roland , HAUGHAN, Alan, Findlay , MATTEUCCI, Mizio , OWENS, Andrew, Pate , RAPHY, Gilles , SHARPE, Andrew

IPC分类号： C07D487/04 , C07D495/04 , A61K31/522 , A61P29/00 , A61P31/00 , A61P37/00 , A61P9/02 , A61P25/28 , A61P3/00 , A61P35/00 , A61P25/00 , A61P27/02

CPC分类号： C07D487/04 , C07D495/04

7.

发明公开
FUSED BICYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS 审中-公开
标题翻译：稠合二环吡唑衍生物作为激酶抑制剂

公开(公告)号：EP2432784A1

公开(公告)日：2012-03-28

申请号：EP10721535.2

申请日：2010-05-19

申请人： UCB Pharma, S.A.

发明人： ALLEN, Daniel, Rees , BROWN, Julien, Alistair , BÜRLI, Roland , HAUGHAN, Alan, Findlay , LANGHAM, Barry, John , MATTEUCCI, Mizio , OWENS, Andrew, Pate , RAPHY, Gilles , SHARPE, Andrew

IPC分类号： C07D487/04 , A61K31/519 , A61P35/00 , A61P25/28 , A61P37/00

CPC分类号： C07D487/04

摘要： A series of substituted pyrazolo[l,5-α][l,3,5]triazine and pyrazolo[l,5-αj- pyrimidine derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. Formula (I).