公开(公告)号：EP2493926A1

公开(公告)日：2012-09-05

申请号：EP10770839.8

申请日：2010-10-27

申请人： UCB Pharma, S.A.

发明人： MILLER, Karen Margrete ,  DE RYCK, Marc Roger ,  WOLFF, Christian Gilbert J. ,  LAWSON, Alastair David Griffiths ,  FINNEY, Helene Margaret ,  BAKER, Terence Seward

IPC分类号： C07K16/28

摘要： A Nav1.7 binding entity that after binding functionally modifies the activity of the ion channel, in particular an anti-Nav1.7 antibody or binding fragment thereof, pharmaceutical compositions comprising said antibodies, use of the antibodies and compositions comprising the same, in treatment, for example in the treatment/modulation of pain and processes for generating and preparing said antibodies.

摘要翻译： 结合后的Nav1.7结合实体功能性地修饰离子通道的活性，特别是抗Nav1.7抗体或其结合片段，包含所述抗体的药物组合物，抗体及其组合物在治疗中的用途 ，例如在疼痛的治疗/调节中以及产生和制备所述抗体的方法。

公开(公告)号：EP2493928A1

公开(公告)日：2012-09-05

申请号：EP10771436.2

申请日：2010-10-27

申请人： UCB Pharma, S.A.

发明人： MILLER, Karen Margrete ,  DE RYCK, Marc Roger ,  WOLFF, Christian Gilbert J. ,  LAWSON, Alastair David Griffiths ,  FINNEY, Helene Margaret ,  BAKER, Terence Seward

IPC分类号： C07K16/28

摘要： An anti-E1 ion channel antibody or binding fragment thereof, pharmaceutical compositions comprising said antibodies, use of the antibodies and compositions comprising the same, in treatment, for example in the treatment/modulation of pain and processes for generating and preparing said antibodies.

摘要翻译： 抗E1离子通道抗体或其结合片段，包含所述抗体的药物组合物，抗体及其组合物的使用，例如用于治疗/调节疼痛以及产生和制备所述抗体的方法。