公开(公告)号：EP3161167A4

公开(公告)日：2018-04-18

申请号：EP15814937

申请日：2015-06-23

申请人： UNIV HONG KONG CHINESE

发明人： CHIM STEPHEN SIU CHUNG ,  CHEUNG CHEE YIN ,  CHEUNG WAN CHEE ,  MENG MENG ,  LEUNG TAK YEUNG ,  LEE KEUN YOUNG

IPC分类号： C12Q1/68

CPC分类号： C12Q1/689 ,  C12Q1/6883 ,  C12Q2600/158 ,  C12Q2600/16

摘要： It provides a method for predicting the risk of an adverse pregnancy or neonatal outcome for a pregnant subject by detecting the elevated level of bacteria from one or more selected bacterial taxa (e.g., genera or species). A kit useful for such a method is also provided. In addition, it provides a method for determining the risk of having advanced cervical dilation and/or premature cervical shortening based on differentially abundant bacterial taxa.

公开(公告)号：EP1859051A4

公开(公告)日：2009-08-05

申请号：EP06722066

申请日：2006-03-17

申请人： UNIV HONG KONG CHINESE

发明人： LO YUK-MING DENNIS ,  CHIU ROSSA WAI KWUN ,  CHIM STEPHEN SIU CHUNG ,  TSUI NANCY BO YIN

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/16

摘要： Methods and kits are provided for diagnosing, monitoring, or predicting preeclaimpsia in a pregnant woman, trisomy 18 and trisomy 21 in a fetus, as well as for detecting pregnancy in a woman, by quantitatively measuring in the maternal blood the amount of one or more RNA species derived from a set of genetic loci and comparing the amount of the RNA species with a standard control.