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公开(公告)号:EP2349279A4
公开(公告)日:2013-12-25
申请号:EP09829428
申请日:2009-10-19
发明人: MOCHLY-ROSEN DARIA , CHEN CHE-HONG , YANG WENJIN
IPC分类号: C07D413/14 , A61K31/67 , C07C233/29 , C07D241/20 , C07D261/08 , C07D261/14 , C07D317/58 , C07D317/60 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12 , C07D487/04 , C07D487/14 , C07D491/052
CPC分类号: A61K31/422 , A61K31/4025 , A61K31/4188 , A61K31/4439 , A61K31/4965 , A61K31/497 , A61K31/5025 , A61K31/519 , A61K31/55 , A61K45/06 , C07C233/29 , C07D241/18 , C07D241/20 , C07D261/08 , C07D261/14 , C07D317/58 , C07D317/60 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D487/04 , C07D491/052
摘要: The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (ALDH) enzymatic activity, as well as compositions and formulations comprising the compounds. The present disclosure provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition.
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2.METHODS AND COMPOSITIONS FOR MODULATING MITOCHONDRIAL ALDEHYDE DEHYDROGENASE-2 审中-公开
标题翻译: 方法和组合物调制线粒体乙醛脱氢酶2公开(公告)号:EP1702213A4
公开(公告)日:2007-07-18
申请号:EP04813603
申请日:2004-12-08
发明人: MOCHLY-ROSEN DARIA , CHEN CHE-HONG
IPC分类号: G01N33/53 , A61K48/00 , C12Q1/32 , G01N33/50 , G01N33/566 , G01N33/573
CPC分类号: G01N33/573 , G01N33/5008 , G01N33/566 , G01N2500/00
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3.
公开(公告)号:EP2337563A4
公开(公告)日:2012-09-12
申请号:EP09812233
申请日:2009-09-03
发明人: YANG WENJIN , CHEN CHE-HONG , MOCHLY-ROSEN DARIA
IPC分类号: C07D405/12 , A61K9/00 , A61K31/33 , A61K31/44
CPC分类号: A61K31/443 , C07D405/12
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4.MITOCHONDRIAL ALDEHYDE DEHYDROGENASE-2 MODULATORS AND METHODS OF USE THEREOF 有权
标题翻译: 线粒体乙醛脱氢酶2调制器和其使用方法公开(公告)号:EP2126574A4
公开(公告)日:2012-02-22
申请号:EP08726601
申请日:2008-03-07
发明人: MOCHLY-ROSEN DARIA , CHEN CHE-HONG
IPC分类号: C07D317/58 , C07D405/12
CPC分类号: C07D317/58 , C07D405/12
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