专利检索 ap:("UNIV OF IOWA RESEARCH FOUNDATION" OR "THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS A BODY CORPORATE AND POLITIC OF THE STATE OF ILLINOIS") AND inv:"GIANGRANDE PALOMA H" 第 1 页

1.

发明公开
OLIGONUCLEOTIDE-BASED PROBES FOR DETECTION OF CIRCULATING TUMOR CELL NUCLEASES 审中-公开

公开(公告)号：EP3286339A2

公开(公告)日：2018-02-28

申请号：EP16784083

申请日：2016-04-25

申请人： UNIV OF IOWA RESEARCH FOUNDATION , THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS A BODY CORPORATE AND POLITIC OF THE STATE OF ILLINOIS

发明人： GIANGRANDE PALOMA H , MCNAMARA JAMES O , DICKEY DAVID D , OZER HOWARD , KRUSPE SVEN

IPC分类号： C12Q1/68 , G01N33/50

CPC分类号： C12Q1/68 , C12Q1/6816 , C12Q1/6886 , C12Q2525/117 , C12Q2525/125

摘要： The present invention relates to a rapid detection of circulating tumor cell (CTC)-associated nuclease activity with chemically modified nuclease substrate probes and compositions useful in detection assays.