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1.发明公开A PROCESS FOR THE PREPARATION OF 4-(2-DIPROPYLAMINOETHYL)-1,3-DIHYDRO-2H-INDOL-2-ONE HYDROCHLORIDE 有权用于4-（2-二丙基氨基乙基）]制造方法-1,3-二氢-2H-吲哚-2-酮盐酸盐
公开(公告)号：EP1706113A1
公开(公告)日：2006-10-04
申请号：EP04806731.8
申请日：2004-07-16
申请人： USV Limited
发明人： TARUR, Venkatasubramanian Radhakrishnan , SATHE, Dhananjay Govind , MONDKAR, Harish Kashinath , BHOPALKAR, Rajesh Ganpat , PATIL, Samadhan Daulat
IPC分类号： A61K31/4035 , C07D209/48 , C07D403/06 , C07D209/34 , A61K31/4045 , A61P25/16
CPC分类号： C07D209/48 , C07D209/34
摘要： The present invention discloses a novel process and novel intermediates for the Preparation of 4-[2-(di -n-propyl amino) ethyl]-1,3-dihydro-2H-indol-2-one, commonly known as Ropinirole (I) and pharmaceutical composition comprising the same. Further the present invention also discloses a method of treatment for cardiovascular disorders and Parkinson’s disease.
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2.发明授权A PROCESS FOR THE PREPARATION OF 4-(2-DIPROPYLAMINOETHYL)-1,3-DIHYDRO-2H-INDOL-2-ONE HYDROCHLORIDE 有权用于4-（2-二丙基氨基乙基）]制造方法-1,3-二氢-2H-吲哚-2-酮盐酸盐
公开(公告)号：EP1706113B1
公开(公告)日：2008-12-10
申请号：EP04806731.8
申请日：2004-07-16
申请人： USV Limited
发明人： TARUR, Venkatasubramanian Radhakrishnan , SATHE, Dhananjay Govind , MONDKAR, Harish Kashinath , BHOPALKAR, Rajesh Ganpat , PATIL, Samadhan Daulat
IPC分类号： A61K31/4035 , C07D209/48 , C07D403/06 , C07D209/34 , A61K31/4045 , A61P25/16
CPC分类号： C07D209/48 , C07D209/34
摘要： The present invention discloses a novel process and novel intermediates for the Preparation of 4-[2-(di -n-propyl amino) ethyl]-1,3-dihydro-2H-indol-2-one, commonly known as Ropinirole (I) and pharmaceutical composition comprising the same. Further the present invention also discloses a method of treatment for cardiovascular disorders and Parkinson’s disease.
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3.发明公开
公开(公告)号：EP2064252A2
公开(公告)日：2009-06-03
申请号：EP07866693.0
申请日：2007-08-31
申请人： USV Limited
发明人： HEDGE, Deepak Anant , CHOUDHARY, Varsha Shashank , TARUR, Radhakrishnan Venkatasubramanian , SATHE, Dhananjay Govind , MONDKAR, Harish, Kashinath , PATIL, Samadhan Daulat , THOOVARA, Sasikumar Mohan , BHIDE, Yogesh Sharad
CPC分类号： A61K31/785 , A61K9/284 , A61K9/2846 , A61K9/2866 , C08F8/02 , C08F8/08 , C08F126/02
摘要： Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.
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