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1.发明授权COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF AUTOIMMUNE CONDITIONS 有权用于预防合剂和方法，自身免疫性疾病的治疗
公开(公告)号：EP2131856B1
公开(公告)日：2014-09-17
申请号：EP08731723.6
申请日：2008-03-07
发明人： SANTAMARIA, Pere , MOORE, Anna
IPC分类号： A61K39/00 , A61K39/385 , A61P37/00 , A61P37/06
CPC分类号： A61K39/0008 , A61K9/5094 , A61K39/385 , A61K47/6923 , A61K47/6929 , A61K2039/55555 , A61K2039/572 , A61K2039/60 , A61K2039/605 , A61K2039/6093 , A61K2039/627 , G01N33/54313 , G01N33/564 , G01N33/56972 , G01N2333/70539 , G01N2800/042
摘要： The methods include selectively reducing or expanding T cells according to the antigenic specificity of the T cells. Therefore, the present invention can be used to reduce or eliminate pathogenic T cells that recognize autoantigens, such as beta cell specific T cells. As such, the present invention can be used to prevent, treat or ameliorate autoimmune diseases such as IDDM. Furthermore, the present invention can be used to expand desirable T cells, such as anti-pathogenic T cells to prevent, treat and/or ameliorate autoimmune diseases.
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2.发明公开COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF AUTOIMMUNE CONDITIONS 审中-公开预防和治疗自身免疫病的组合物和方法
公开(公告)号：EP3269384A1
公开(公告)日：2018-01-17
申请号：EP17173410.6
申请日：2008-03-07
发明人： SANTAMARIA, Pere , MOORE, Anna
IPC分类号： A61K39/00 , A61K39/385 , A61P37/00 , A61P37/06
CPC分类号： A61K39/0008 , A61K9/5094 , A61K39/385 , A61K47/6923 , A61K47/6929 , A61K2039/55555 , A61K2039/572 , A61K2039/60 , A61K2039/605 , A61K2039/6093 , A61K2039/627 , G01N33/54313 , G01N33/564 , G01N33/56972 , G01N2333/70539 , G01N2800/042
摘要： The methods include selectively reducing or expanding T cells according to the antigenic specificity of the T cells. Therefore, the present invention can be used to reduce or eliminate pathogenic T cells that recognize autoantigens, such as beta cell specific T cells. As such, the present invention can be used to prevent, treat or ameliorate autoimmune diseases such as IDDM. Furthermore, the present invention can be used to expand desirable T cells, such as anti-pathogenic T cells to prevent, treat and/or ameliorate autoimmune diseases.
摘要翻译： 该方法包括根据T细胞的抗原特异性选择性地减少或扩增T细胞。 因此，本发明可用于减少或消除识别自身抗原的致病性T细胞，如β细胞特异性T细胞。 这样，本发明可用于预防，治疗或改善自身免疫疾病如IDDM。 此外，本发明可以用于扩展期望的T细胞，如抗病原性T细胞以预防，治疗和/或改善自身免疫性疾病。
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3.发明公开COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF AUTOIMMUNE CONDITIONS 有权用于预防合剂和方法，自身免疫性疾病的治疗
公开(公告)号：EP2131856A2
公开(公告)日：2009-12-16
申请号：EP08731723.6
申请日：2008-03-07
发明人： SANTAMARIA, Pere , MOORE, Anna
IPC分类号： A61K39/00 , A61K39/385 , A61P37/00 , A61P37/06
CPC分类号： A61K39/0008 , A61K9/5094 , A61K39/385 , A61K47/6923 , A61K47/6929 , A61K2039/55555 , A61K2039/572 , A61K2039/60 , A61K2039/605 , A61K2039/6093 , A61K2039/627 , G01N33/54313 , G01N33/564 , G01N33/56972 , G01N2333/70539 , G01N2800/042
摘要： The methods include selectively reducing or expanding T cells according to the antigenic specificity of the T cells. Therefore, the present invention can be used to reduce or eliminate pathogenic T cells that recognize autoantigens, such as beta cell specific T cells. As such, the present invention can be used to prevent, treat or ameliorate autoimmune diseases such as IDDM. Furthermore, the present invention can be used to expand desirable T cells, such as anti-pathogenic T cells to prevent, treat and/or ameliorate autoimmune diseases.
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