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公开(公告)号：EP4127189A1
公开(公告)日：2023-02-08
申请号：EP21721256.2
申请日：2021-03-30
发明人： FULLER, Matthew, Scott , WADSWORTH, Samuel , CLARK, Kelly, Reed , DAUGHERTY, Sean, Christopher , CRAIG, Stewart
IPC分类号： C12N15/86 , C12N15/113 , C12N9/00
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公开(公告)号：EP3861131A1
公开(公告)日：2021-08-11
申请号：EP19869846.6
申请日：2019-10-01
发明人： FULLER, Matthew Scott , WADSWORTH, Samuel , CLARK, Kelly, Reed , DAUGHERTY, Sean Christopher , CRAIG, Stewart
IPC分类号： C12Q1/68 , C12N15/861 , C12N15/09 , C12N15/11
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公开(公告)号：EP4269579A2
公开(公告)日：2023-11-01
申请号：EP23196931.2
申请日：2020-01-03
IPC分类号： C12N9/64
摘要： This application relates to adeno-associated viral vectors encoding a truncated yet functional ATP7B for use in gene therapy for treating Wilson disease (WD). The truncated ATP7B described herein has several advantages over the wild-type ATP7B such as higher efficacy and improved manufacturing yield.
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公开(公告)号：EP3898981A1
公开(公告)日：2021-10-27
申请号：EP19845789.7
申请日：2019-12-18
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公开(公告)号：EP4384196A1
公开(公告)日：2024-06-19
申请号：EP22782794.6
申请日：2022-08-10
发明人： FULLER, Matthew Scott , STOICA, Lorelei Ioana , TIERNAN, Aubrey Rose , CLARK, Kelly Reed , WADSWORTH, Samuel
IPC分类号： A61K35/76 , C07K14/47 , C12N15/864 , C12N15/67
CPC分类号： C07K14/4707 , C07K14/4708 , C12N15/67 , C12N15/86 , C12N2750/1414320130101 , C12N2830/00820130101
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公开(公告)号：EP4269579A3
公开(公告)日：2024-01-24
申请号：EP23196931.2
申请日：2020-01-03
摘要： This application relates to adeno-associated viral vectors encoding a truncated yet functional ATP7B for use in gene therapy for treating Wilson disease (WD). The truncated ATP7B described herein has several advantages over the wild-type ATP7B such as higher efficacy and improved manufacturing yield.
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公开(公告)号：EP3906066A1
公开(公告)日：2021-11-10
申请号：EP20704633.5
申请日：2020-01-03
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8.发明公开
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