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1.发明公开METHOD FOR THE DIAGNOSIS AND PROGNOSIS OF MELANOMA SKIN CANCER 审中-公开VERFAHREN ZUR DIAGNOSE UND PROGNOSE VON MELANOMEM HAUTKREBS
公开(公告)号：EP3051291A1
公开(公告)日：2016-08-03
申请号：EP14796149.4
申请日：2014-09-26
发明人： BOYANO LÓPEZ, María Dolores , ARROLLO BERDUGO, Yoana , ALONSO ALEGRE, Santos , ASUMENDI MALLEA, Aintzane , PÉREZ-YARZA PÉREZ-IREZABAL, Gorka , CAREAGA ALZAGA, Jesús María , GARDEAZABAL GARCÍA, Jesús , IZU BELLOSO, Rosa , DÍAZ RAMÓN, José Luis , ACEBO MARIÑAS, Elvira , SÁNCHEZ DÍEZ, Ana , MARTÍNEZ DELIZARDUY, Íñigo , RATÓN NIETO, Juan Antonio
IPC分类号： G01N33/574
CPC分类号： G01N33/57407 , G01N33/57484
摘要： The present invention relates to an in vitro method for diagnosing cutaneous melanoma and an in vitro method for differentiating benign nevus from melanoma in a cutaneous lesion based on determining the expression level of PIR. Additionally, the invention relates to an in vitro method for determining the probability of metastasis in a subject diagnosed with cutaneous melanoma based on determining the expression level of PIR, BCL2.
摘要翻译： 本发明涉及一种用于诊断皮肤黑色素瘤的体外方法和用于根据确定PIR的表达水平在皮肤病变中鉴别良性痣与黑素瘤的体外方法。 此外，本发明涉及一种用于基于确定PIR，BCL2的表达水平来确定诊断为皮肤黑素瘤的受试者的转移概率的体外方法。
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公开(公告)号：EP3051291B1
公开(公告)日：2019-01-30
申请号：EP14796149.4
申请日：2014-09-26
发明人： BOYANO LÓPEZ, María Dolores , ARROLLO BERDUGO, Yoana , ALONSO ALEGRE, Santos , ASUMENDI MALLEA, Aintzane , PÉREZ-YARZA PÉREZ-IREZABAL, Gorka , CAREAGA ALZAGA, Jesús María , GARDEAZABAL GARCÍA, Jesús , IZU BELLOSO, Rosa , DÍAZ RAMÓN, José Luis , ACEBO MARIÑAS, Elvira , SÁNCHEZ DÍEZ, Ana , MARTÍNEZ DELIZARDUY, Íñigo , RATÓN NIETO, Juan Antonio
IPC分类号： G01N33/574
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