公开(公告)号：EP3477305A1

公开(公告)日：2019-05-01

申请号：EP17198330.7

申请日：2017-10-25

申请人： Universität Heidelberg

发明人： Hildebrand, Dagmar ,  Heeg, Klaus ,  Uhle, Florian ,  Weigand, Markus A.

IPC分类号： G01N33/68

摘要： The invention refers to a method for in vitro diagnosis and/or prognosis of a severe infection comprising determining delta-like ligand 1 protein or a nucleotide sequence coding for delta-like ligand 1 protein in a biological sample wherein an elevated level of expression of delta-like ligand 1 protein or a nucleotide sequence coding for delta-like ligand 1 protein is indicative of a severe infection; and the use of delta-like ligand 1 protein as a biomarker for in vitro diagnosis and/or prognosis of a severe infection such as sepsis.