专利检索 ap:("Universita' degli Studi di Milano" OR "Fondazione IRCCS Istituto Nazionale dei Tumori" OR "CISI Scrl" OR "Fondazione Cariplo") AND inv:"MASTRANGELO, Eloise" 第 1 页

1.

发明授权
HOMO- AND HETERODIMERIC SMAC MIMETIC COMPOUNDS AS APOPTOSIS INDUCERS 有权
标题翻译： HOMO和表格异MIME SMAC化合物作为细胞凋亡诱导剂

公开(公告)号：EP2817322B1

公开(公告)日：2016-04-20

申请号：EP12865538.8

申请日：2012-02-20

申请人： Universita' degli Studi di Milano , Fondazione IRCCS Istituto Nazionale dei Tumori , CISI Scrl , Fondazione Cariplo

发明人： SENECI, Pierfausto , BELVISI, Laura , COSSU, Federica , DELIA, Domenico , DRAGO, Carmelo , LECIS, Daniele , MAIORANA, Stefano , MANZONI, Leonardo, Pierpaolo , MASTRANGELO, Eloise , MILANI DE MAYO DE MARI, Mario , PEREGO, Paola Maria Chiara , VASILE, Francesca

IPC分类号： C07K5/083 , C07K5/103 , C07D487/04 , A61P35/00 , A61K31/5517

CPC分类号： A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D519/00 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/1005 , C07K5/1008 , C07K5/101

2.

发明公开
NEW HOMO- AND HETERODIMERIC SMAC MIMETIC COMPOUNDS AS APOPTOSIS INDUCERS 有权
标题翻译： HOMO和表格异MIME SMAC化合物作为细胞凋亡诱导剂

公开(公告)号：EP2817322A2

公开(公告)日：2014-12-31

申请号：EP12865538.8

申请日：2012-02-20

申请人： Universita' degli Studi di Milano , Fondazione IRCCS Istituto Nazionale dei Tumori , CISI Scrl , Fondazione Cariplo

发明人： SENECI, Pierfausto , BELVISI, Laura , COSSU, Federica , DELIA, Domenico , DRAGO, Carmelo , LECIS, Daniele , MAIORANA, Stefano , MANZONI, Leonardo, Pierpaolo , MASTRANGELO, Eloise , MILANI DE MAYO DE MARI, Mario , PEREGO, Paola Maria Chiara , VASILE, Francesca

IPC分类号： C07K5/083 , C07D487/04 , A61P35/00 , A61K31/5517

CPC分类号： A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D519/00 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/1005 , C07K5/1008 , C07K5/101

摘要： The present invention relates to conformationally constrained homo- and heterodimeric mimetics of Smac with function as inhibitors of Inhibitor of Apoptosis Proteins (IAPs), the invention also relates to the use of these compounds in therapy, wherein the induction of apoptotic cell death is beneficial, especially in the treatment of cancer, alone or in combination with other active ingredients.

3.

发明公开
NEW SMAC MIMETIC COMPOUNDS AS APOPTOSIS INDUCERS 审中-公开
标题翻译：新SMAC MIME TABLES化合物作为细胞凋亡TIMER

公开(公告)号：EP2220088A2

公开(公告)日：2010-08-25

申请号：EP08847147.9

申请日：2008-11-05

申请人： Universita' degli Studi di Milano , Fondazione IRCCS Istituto Nazionale dei Tumori

发明人： SCOLASTICO, Carlo , MANZONI, Leonardo, Pierpaolo , SENECI, Pierfausto , BELVISI, Laura , DELIA, Domenico , BOLOGNESI, Martino , MASTRANGELO, Eloise , MILANI, Mario De Mayo De Mari , MOTTO, Llaria , DRAGO, Carmelo

IPC分类号： C07D487/04 , A61K31/5517 , A61P35/00

CPC分类号： C07D487/04 , C07K5/0808

摘要： The present invention relates to compounds conformationally constrained mimetics of Smac with function as inhibitors of Inhibitor of Apoptosis Proteins (IAPs), the invention also relates to the use of these compounds in therapy, wherein the induction of apoptotic cell death is beneficial, especially in the treatment of cancer, alone or in combination with other active ingredients.