公开(公告)号：EP4497439A1

公开(公告)日：2025-01-29

申请号：EP23382792.2

申请日：2023-07-28

Applicant: Universitat de les Illes Balears

Inventor： COSTA BAUZÀ, Antonia ,  GRASES FREIXEDAS, Felix

IPC: A61K31/522 ,  A61K31/165 ,  A61K31/195 ,  A61K31/343 ,  A61K31/4152 ,  A61K31/4196 ,  A61K31/426 ,  A61K31/519 ,  A61P19/02 ,  A61P19/06

Abstract: The present invention provides compound of formula (I) or a pharmaceutically acceptable salt thereof, for use in the prevention and/or treatment of a disease or disorder associated with the crystallization of monosodium urate monohydrate, wherein R 1 and R 2 are different and are selected from -H and -(C 1 -C 6 )alkyl; and R 3 is selected from -H and =O. The invention also provides an in vitro method for eliminating and/or preventing the formation of monosodium urate monohydrate crystals in a composition, and an i n vitro use of a compound of formula (I) for eliminating and/or preventing the formation of monosodium urate monohydrate crystals.

公开(公告)号：EP2022501A1

公开(公告)日：2009-02-11

申请号：EP07765887.0

申请日：2007-05-30

Applicant: Universitat de les Illes Balears

Inventor： GRASES FREIXEDAS, Felix ,  SANCHIS CORTES, Pilar ,  COSTA-BAUZÁ, Antonia ,  PERELLÓ BESTARD, Joan ,  PRIETO ALMIRALL, Rafael Mará ,  ISERN AMENGUAL, Bernat ,  GARCÍA GONZÁLEZ, Ramón

IPC: A61K31/6615 ,  A61P19/10

CPC classification number: A61K31/6615

Abstract: The present invention relates to the utilisation of myo-inositol hexaphosphate or pharmaceutically-acceptable salts thereof for the manufacture of a medicament destined for the prevention or treatment of a disease associated with the dissolution of crystals of calcium salts, in particular osteoporosis. Said compound may be utilised in the manufacture of functional foods, dietetic complements, vitamin complements or nutritional complements or food complements or phytotherapeutic products having properties of inhibition of dissolution of crystals of calcium salts.

Abstract translation: 本发明涉及肌醇六磷酸酯或其药学上可接受的盐的使用，其用于去往与钙盐晶体的溶解，特别是骨质疏松症有关的疾病的预防或治疗的药物中的用途。 所述化合物可以在功能性食品，营养补，维生素互补或营养补或食品补或具有抑制钙盐晶体溶解的性质植物治疗产品的制造中使用。

公开(公告)号：EP2022501B1

公开(公告)日：2019-08-14

申请号：EP07765887.0

申请日：2007-05-30

Applicant: Universitat de les Illes Balears

Inventor： GRASES FREIXEDAS, Felix ,  SANCHIS CORTES, Pilar ,  COSTA-BAUZÁ, Antonia ,  PERELLÓ BESTARD, Joan ,  PRIETO ALMIRALL, Rafael Mará ,  ISERN AMENGUAL, Bernat ,  GARCÍA GONZÁLEZ, Ramón

IPC: A61K31/6615 ,  A61P19/10 ,  A23L33/10