公开(公告)号：EP2404627A1

公开(公告)日：2012-01-11

申请号：EP10305769.1

申请日：2010-07-09

申请人： Universite De Nantes I ,  Chu Nantes

发明人： Hoornaert, Alain ,  Layrolle, Pierre ,  Sohier, Jérôme

IPC分类号： A61L31/14

CPC分类号： A61B17/8085 ,  A61L31/146 ,  A61L31/148 ,  A61L2400/12 ,  A61L2430/02

摘要： Bone regeneration membrane (1) comprising:
- a dense layer (2) made of resorbable polymer, said dense layer (2) having first and second opposite surfaces and being adapted to form a barrier to cells and soft tissues,
- a nanofibrillar layer (3) made of resorbable polymer and attached to the first surface of the dense layer (2), said nanofibrillar layer comprising fibers having a diameter of nanometer size, said fibers being interlaced so as to present an average pore size greater than 10 µm to allow cell permeability and bone tissue regeneration.

摘要翻译： 骨再生膜（1）包括： - 由可再吸收的聚合物制成的致密层（2），所述致密层（2）具有第一和第二相对表面并适于形成对细胞和软组织的屏障， - 纳米纤维层 3）由可再吸收的聚合物制成并且附着到致密层（2）的第一表面，所述纳米纤维层包含直径为纳米尺寸的纤维，所述纤维交织以提供大于10μm的平均孔径，以允许 细胞通透性和骨组织再生。