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公开(公告)号：EP4188399A2
公开(公告)日：2023-06-07
申请号：EP21755720.6
申请日：2021-07-29
申请人： Universiteit Gent
发明人： CRABBÉ, Aurélie , COENYE, Tom , RIGAUTS, Charlotte
IPC分类号： A61K35/74 , A61P1/00 , A61P1/04 , A61P11/00 , A61P11/02 , A61P11/06 , A61P11/12 , A61P17/00 , A61P17/06 , A61P17/08 , A61P17/10 , A61K31/047 , A61K31/661 , A61K31/7008 , A61K31/7016 , A61K31/7034
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公开(公告)号：EP3166955A1
公开(公告)日：2017-05-17
申请号：EP15736232.8
申请日：2015-07-06
申请人： Universiteit Gent
IPC分类号： C07H5/06 , A61K31/7008 , A61P31/00 , C07D405/12 , C07H13/04 , C07H15/18 , C07D493/04 , C07D307/20
CPC分类号： C07H13/04 , A61K31/357 , A61K31/404 , A61K31/443 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/7012 , A61K45/06 , C07D307/20 , C07D405/12 , C07D493/04 , C07H15/18 , Y02P20/582
摘要： The present invention relates to hamamelitannin analogues, pharmaceutical compositions comprising the same, and combinations thereof with anti-microbial agents such as antibiotics or disinfectants. It in particular relates to the use of the compounds, compositions and combinations according to this invention in human or veterinary medicine, more in particular for use in the prevention and/or treatment of bacterial infections, such as Staphylococcus aureus infections, in humans or animals.
摘要翻译： 本发明涉及hamamelitannin类似物，包含其的药物组合物及其与抗微生物剂（例如抗生素或消毒剂）的组合。 本发明尤其涉及本发明化合物，组合物和组合在人或兽医学中的用途，更特别地用于预防和/或治疗人或动物中的细菌感染例如金黄色葡萄球菌感染 。
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公开(公告)号：EP3322447A1
公开(公告)日：2018-05-23
申请号：EP16734284.9
申请日：2016-06-29
申请人： Universiteit Gent
IPC分类号： A61K41/00
CPC分类号： A61K41/0028 , A61K9/127 , A61N5/062 , A61N2005/0659 , A61N2005/0661 , A61N2005/067 , A61P1/02
摘要： A method for altering and/or disrupting a microbiological film is described. The method comprises introducing a composition into a microbiological film, the composition comprising nano- or microparticles having an electron density that can couple with a photon wave of electromagnetic radiation. The method also comprises irradiating said microbiological film by said electromagnetic radiation such as to form a vapour bubbles using said nano- or microparticles in said microbiological biofilm, thereby generating a mechanical force for locally altering and/or disrupting said microbiological film when said vapour bubbles expand and/or collapse.
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公开(公告)号：EP3166955B1
公开(公告)日：2018-05-02
申请号：EP15736232.8
申请日：2015-07-06
申请人： Universiteit Gent
IPC分类号： C07H5/06 , A61K31/7008 , A61P31/00 , C07D405/12 , C07H13/04 , C07H15/18 , C07D493/04 , C07D307/20
CPC分类号： C07H13/04 , A61K31/357 , A61K31/404 , A61K31/443 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/7012 , A61K45/06 , C07D307/20 , C07D405/12 , C07D493/04 , C07H15/18 , Y02P20/582
摘要： The present invention relates to hamamelitannin analogues, pharmaceutical compositions comprising the same, and combinations thereof with anti-microbial agents such as antibiotics or disinfectants. It in particular relates to the use of the compounds, compositions and combinations according to this invention in human or veterinary medicine, more in particular for use in the prevention and/or treatment of bacterial infections, such as Staphylococcus aureus infections, in humans or animals.
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