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公开(公告)号:EP3029467B1
公开(公告)日:2020-01-08
申请号:EP15202190.3
申请日:2009-09-22
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公开(公告)号:EP3029467A1
公开(公告)日:2016-06-08
申请号:EP15202190.3
申请日:2009-09-22
发明人: GUNDLACH, Jens, H. , NIEDERWEIS, Michael , BUTLER, Thomas, Z. , PAVLENOK, Mikhail , TROLL, Mark, A. , SUKUMARAN, Suja
摘要: Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.
摘要翻译: 本文提供了耻垢分枝杆菌孔蛋白纳米孔,包含这些纳米孔的系统,以及使用和制造这些纳米孔的方法。 这种纳米孔可以是野生型MspA孔蛋白,突变MspA孔蛋白,野生型MspA旁系同源孔蛋白,野生型MspA同源孔蛋白,突变MspA旁系同源孔蛋白,突变MspA同源孔蛋白或单链Msp孔蛋白。 还提供了能够诱导Msp孔蛋白表达的细菌菌株。
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公开(公告)号:EP2344891A2
公开(公告)日:2011-07-20
申请号:EP09815404.0
申请日:2009-09-22
发明人: GUNDLACH, Jens, H. , NIEDERWEIS, Michael , BUTLER, Thomas, Z. , PAVLENOK, Mikhail , TROLL, Mark, A.
CPC分类号: C12Q1/6869 , A61K39/00 , A61K39/04 , C07K14/35 , C12N13/00 , G01N24/00 , G01N27/44704 , G01N27/44791 , G01N33/48721 , G01N33/6872 , C12Q2523/31 , C12Q2565/631
摘要: Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.
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公开(公告)号:EP3686602A1
公开(公告)日:2020-07-29
申请号:EP19212121.8
申请日:2009-09-22
发明人: GUNDLACH, Jens, H. , NIEDERWEIS, Michael , BUTLER, Thomas, Z. , PAVLENOK, Mikhail , TROLL, Mark, A. , SUKUMARAN, Suja
摘要: Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.
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公开(公告)号:EP2344891B1
公开(公告)日:2016-03-16
申请号:EP09815404.0
申请日:2009-09-22
发明人: GUNDLACH, Jens, H. , NIEDERWEIS, Michael , BUTLER, Thomas, Z. , PAVLENOK, Mikhail , TROLL, Mark, A. , SUKUMARAN, Suja
CPC分类号: C12Q1/6869 , A61K39/00 , A61K39/04 , C07K14/35 , C12N13/00 , G01N24/00 , G01N27/44704 , G01N27/44791 , G01N33/48721 , G01N33/6872 , C12Q2523/31 , C12Q2565/631
摘要: Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.
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