NUCLEAR MAGNETIC RESONANCE SENSING DEVICE AND NUCLEAR MAGNETIC RESONANCE SENSING METHOD

    公开(公告)号:EP4435423A1

    公开(公告)日:2024-09-25

    申请号:EP22895171.1

    申请日:2022-08-12

    IPC分类号: G01N24/00

    CPC分类号: G01N24/00

    摘要: [Problems] A low-level NMR signal is accurately detected and nuclear magnetic resonance sensing having high resolution is performed.
    [Solution] A nuclear magnetic resonance sensing part 1 applies a high frequency magnetic field based on an RF signal to a target object and generates an observation signal with a frequency that is shifted from a frequency of the RF signal by a frequency of an NMR signal. A mixer part 6 generates an IF demodulation signal including the NMR signal. A low-pass filter 7 passes a low frequency component of the IF demodulation signal. In a digitizing device 2, a physical field generator generates a magnetic field and so on corresponding to the IF demodulation signal that has passed through the low-pass filter 7, an optical quantum sensor part generates light corresponding to the magnetic field and so on by a sensing member and converts the light into a sensor signal by a photoelectric element, and an analog/digital converter digitizes the sensor signal. The optical quantum sensor part performs a quantum operation with respect to the sensing member and causes the sensing member to generate the light corresponding to the magnetic field and so on.

    DÉTECTEUR D'OBJETS OU DE MATIÈRES NON AUTORISÉES DISSIMULÉS DANS UNE CHAUSSURE
    6.
    发明公开
    DÉTECTEUR D'OBJETS OU DE MATIÈRES NON AUTORISÉES DISSIMULÉS DANS UNE CHAUSSURE 审中-公开
    探测器对象或未经授权的材料隐藏在鞋中

    公开(公告)号:EP3318901A1

    公开(公告)日:2018-05-09

    申请号:EP17208536.7

    申请日:2017-04-14

    IPC分类号: G01V3/12 G01V3/08

    摘要: La présente invention concerne un dispositif détecteur pour la détection d'objets ou matières non autorisés, comprenant une embase support (110) conçue pour recevoir au moins un pied revêtu de sa chaussure, d'un individu à contrôler, le dispositif comprenant en outre des moyens (170) adaptés pour déceler une stratification par empilement vertical, dans la semelle, par détection d'échos successifs suite à une émission d'ondes vers la semelle, des moyens pour definer un signal représentatif de la hauteur estimée de la semelle, des moyens de normalisation du signal issu des moyens de détection d'une stratification verticale (172), sur la base du signal repésentatif de la hauteur estimée de la semelle.

    摘要翻译: 本发明涉及一种用于检测未经授权的物体或材料的检测器装置,包括:支撑基座(110),该支撑基座被设计成接收涂覆有鞋的至少一只脚,要控制的个体,该装置还包括 适于通过垂直堆叠来检测分层的装置(170),所述分层通过检测在向所述鞋底发射波之后的连续回声,用于限定代表所述底板的估计高度的信号的装置, 信号归一化装置基于估计的鞋底高度的代表性信号从垂直分层检测装置(172)获得。

    Method for deciding whether a sample is consistent with an established production norm for heterogeneous products
    9.
    发明公开
    Method for deciding whether a sample is consistent with an established production norm for heterogeneous products 审中-公开
    一种用于确定与用于产生多相产品预定标准样品是否一致的方法

    公开(公告)号:EP2664941A1

    公开(公告)日:2013-11-20

    申请号:EP12168422.9

    申请日:2012-05-17

    IPC分类号: G01R33/46 G01N24/08

    摘要: A method of analysis of a heterogeneous product, for example heparin or heparin derivatives, to define whether said heterogeneous product is consistent with a library of verified heterogeneous samples (Library 1) by analysing the variation, natural or alien.
    The acceptable variation of the heterogeneous product is determined by comparing Library 1 with a second set of verified spectra (Library 2), by use of comparative two-dimensional correlation spectroscopic filtering (comparative 2D-COS-f).
    The method comprises obtaining a one-dimensional complex spectrum, for example 1 H-NMR spectra, of a heterogeneous product and testing if it has features that are greater than features found testing a spectrum from Library 2 against Library 1.
    In a second embodiment comparative 2D-COS-f with iterative random sampling (2D-COS-firs) is applied, which provides a more accurate and stable extraction of aliens/unnatural features.
    The method defines whether a test sample is consistent with a library of production norms of heterogeneous products; determines the acceptance criteria to be considered as normal production for heterogeneous products and detects species alien to the production norms of heterogeneous products.

    摘要翻译: 异构产物的分析的方法,对于实施例的肝素或肝素衍生物,以限定是否所述异构产物是验证异质样品(库1)由成绩的分析变体中,天然的或外来的文库相一致。 异构产物的可接受的变化是确定性的,通过使用比较二维相关光谱滤波的具有第二组验证光谱(图书馆2)的比较库1开采(比较2D COS F)。 该方法包括获得一维复数频谱,例如1个H-NMR光谱,异构产物和测试其是否具有特征并比发现从库2测试光谱针对库1.在第二个对比实施方式的特征更大 2D COS f控制迭代随机抽样(2D-COS-冷杉)被施加,这提供的外星人/非天然特征的更精确和稳定的提取。 该方法定义是否测试样品是具有多相产品的生产规范库相符; bestimmt验收标准被认为是正常的生产异构产品和检测物种的外来异构产品的生产规范。