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公开(公告)号:EP3245514B1
公开(公告)日:2019-07-10
申请号:EP16706122.5
申请日:2016-01-13
申请人: Ustav organicke chemie a biochemie AV CR, v.v.i. , Ustav Makromolekularni Chemie AV CR, v.v.i. , Univerzita Karlova v Praze, Prírodovedecká fakulta
发明人: SACHA, Pavel , KONVALINKA, Jan , SCHIMER, Jiri , KNEDLIK, Tomas , NAVRATIL, Vaclav , TYKVART, Jan , SEDLAK, Frantisek , MAJER, Pavel , CIGLER, Petr , SUBR, Vladimir , ULBRICH, Karel , STROHALM, Jiri
IPC分类号: G01N33/531 , A61K49/00 , C08F20/58 , C08F220/58 , G01N33/532 , G01N33/533 , G01N33/534
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2.MACROMOLECULAR CONJUGATES FOR VISUALIZATION AND SEPARATION OF PROTEINS AND CELLS 审中-公开
标题翻译: 大分子共轭物用于蛋白质和细胞的可视化和分离公开(公告)号:EP3245514A2
公开(公告)日:2017-11-22
申请号:EP16706122.5
申请日:2016-01-13
申请人: Ustav organicke chemie a biochemie AV CR, v.v.i. , Ustav Makromolekularni Chemie AV CR, v.v.i. , Univerzita Karlova v Praze, Prírodovedecká fakulta
发明人: SACHA, Pavel , KONVALINKA, Jan , SCHIMER, Jiri , KNEDLIK, Tomas , NAVRATIL, Vaclav , TYKVART, Jan , SEDLAK, Frantisek , MAJER, Pavel , CIGLER, Petr , SUBR, Vladimir , ULBRICH, Karel , STROHALM, Jiri
IPC分类号: G01N33/531 , A61K49/00 , C08F20/58 , C08F220/58 , G01N33/532 , G01N33/533 , G01N33/534
CPC分类号: G01N33/534 , A61K47/58 , A61K49/0054 , C08F220/58 , C08F2500/01 , G01N33/531 , G01N33/532 , G01N33/533
摘要: A macromolecular water-soluble conjugates based on synthetic copolymers to which at least one affinity tag, at least one imaging probe and at least one targeting ligand are bound via covalent bonds. The macromolecular conjugate may be used in identification, visualization, quantification or isolation of proteins and/or cells.
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公开(公告)号:EP3245513B1
公开(公告)日:2019-07-10
申请号:EP16706121.7
申请日:2016-01-13
申请人: Ustav Organicke Chemie a Biochemie Akademie Ved Ceske Republiky, V.V.I. , Ustav Makromolekularni Chemie AV CR, v.v.i. , Univerzita Karlova v Praze, Prírodovedecká fakulta
发明人: SACHA, Pavel , KONVALINKA, Jan , SCHIMER, Jiri , KNEDLIK, Tomas , SUBR, Vladimir , ULBRICH, Karel , STROHALM, Jiri
IPC分类号: G01N33/531 , G01N33/532 , G01N33/533 , G01N33/534 , C08F8/30
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4.MACROMOLECULAR CONJUGATES FOR ISOLATION, IMMOBILIZATION AND VISUALIZATION OF PROTEINS 审中-公开
标题翻译: 大分子共轭物用于蛋白质的分离,固定和可视化公开(公告)号:EP3245513A2
公开(公告)日:2017-11-22
申请号:EP16706121.7
申请日:2016-01-13
申请人: Ustav Organicke Chemie a Biochemie Akademie Ved Ceske Republiky, V.V.I. , Ustav Makromolekularni Chemie AV CR, v.v.i. , Univerzita Karlova v Praze, Prírodovedecká fakulta
发明人: SACHA, Pavel , KONVALINKA, Jan , SCHIMER, Jiri , KNEDLIK, Tomas , SUBR, Vladimir , ULBRICH, Karel , STROHALM, Jiri
IPC分类号: G01N33/531 , G01N33/532 , G01N33/533 , G01N33/534 , C08F20/58 , C08F220/58
CPC分类号: G01N33/532 , C08F8/30 , G01N33/531 , G01N33/533 , G01N33/534 , G01N33/58 , G01N33/582
摘要: Synthetic macromolecular conjugate for selective interaction with proteins has a synthetic copolymer, and at least one binding group and at least one further group selected from an affinity tag and an imaging probe, and at least one binding group and at least one further group being bound via covalent bond to the synthetic copolymer. The macromolecular conjugate is suitable in particular for identification, visualization, quantification or isolation of proteins and/or cells.
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