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公开(公告)号：EP3219705B1
公开(公告)日：2020-03-11
申请号：EP17154944.7
申请日：2006-12-28
发明人： HURTER, Patricia , GONG, Yuchuan , YOUNG, Christopher R. , CONNELLY, Patrick , ROWE, William , COSTACHE, Adriana , KRAWIEC, Mariusz , FENG, Yushi , TRUDEAU, Martin
IPC分类号： C07D215/56 , A61K31/445
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2.发明授权SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 有权N- [2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧喹啉-3-甲酰胺的固体形式
公开(公告)号：EP1993360B1
公开(公告)日：2017-02-08
申请号：EP06848237.1
申请日：2006-12-28
发明人： HURTER, Patricia , GONG, Yuchuan , YOUNG, Christopher R. , CONNELLY, Patrick , ROWE, William , COSTACHE, Adriana , KRAWIEC, Mariusz , FENG, Yushi , TRUDEAU, Martin
IPC分类号： C07D215/56 , A61K31/445
CPC分类号： A61K31/47 , A61K2300/00 , C07B2200/13 , C07D215/56 , Y10T428/2982
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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3.发明公开
公开(公告)号：EP3708564A1
公开(公告)日：2020-09-16
申请号：EP20156047.1
申请日：2006-12-28
发明人： HURTER, Patricia , GONG, Yuchuan , YOUNG, Christopher R. , CONNELLY, Patrick , ROWE, William , COSTACHE, Adriana , KRAWIEC, Mariusz , FENG, Yushi , TRUDEAU, Martin
IPC分类号： C07D215/56 , A61K31/47
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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4.发明公开PHARMACEUTICAL COMPOSITIONS OF THE AMORPHOUS FORM OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 审中-公开N- [2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧代喹啉-3-甲酰胺的非晶形式的药物组合物
公开(公告)号：EP3219705A1
公开(公告)日：2017-09-20
申请号：EP17154944.7
申请日：2006-12-28
发明人： HURTER, Patricia , GONG, Yuchuan , YOUNG, Christopher R. , CONNELLY, Patrick , ROWE, William , COSTACHE, Adriana , KRAWIEC, Mariusz , FENG, Yushi , TRUDEAU, Martin
IPC分类号： C07D215/56 , A61K31/445
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
摘要翻译： 本发明涉及N- [2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧代喹啉-3-甲酰胺（化合物1）的固体形式，药物组合物 及其方法。
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5.发明公开SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 审中-公开N-固体形式[2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧喹啉-3-甲酰胺
公开(公告)号：EP2222304A2
公开(公告)日：2010-09-01
申请号：EP08832069.2
申请日：2008-09-15
发明人： DEMATTEI, John , FENG, Yushi , HARRISON, Cristian , LOOKER, Adam , MUDUNURI, Praveen , ROEPER, Stefanie , ZHANG, Yuegang
CPC分类号： C07D215/56 , A61K31/47 , A61K45/06 , C07D215/233
摘要： Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide are described herein, including crystalline forms thereof.
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6.发明公开SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 有权N- [2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧喹啉-3-甲酰胺的固体形式
公开(公告)号：EP1993360A2
公开(公告)日：2008-11-26
申请号：EP06848237.1
申请日：2006-12-28
发明人： HURTER, Patricia , GONG, Yuchuan , YOUNG, Christopher R. , CONNELLY, Patrick , ROWE, William , COSTACHE, Adriana , KRAWIEC, Mariusz , FENG, Yushi , TRUDEAU, Martin
IPC分类号： A01N43/40 , A61K31/445
CPC分类号： A61K31/47 , A61K2300/00 , C07B2200/13 , C07D215/56 , Y10T428/2982
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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