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公开(公告)号:EP4038068A1
公开(公告)日:2022-08-10
申请号:EP20789277.9
申请日:2020-09-29
发明人: BOWSHER, Michael S. , GILLIS, Eric P , IWUAGWU, Christiana , NAIDU, B. Narasimhulu , PARCELLA, Kyle E. , PATEL, Manoj
IPC分类号: C07D471/04 , A61K31/519 , A61P31/18
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公开(公告)号:EP3870577A1
公开(公告)日:2021-09-01
申请号:EP19794683.3
申请日:2019-10-22
IPC分类号: C07D403/14 , A61P31/18 , A61K31/517
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公开(公告)号:EP3107917B1
公开(公告)日:2018-08-15
申请号:EP14709808.1
申请日:2014-02-19
发明人: NAIDU, B. Narasimhulu , PATEL, Manoj , D'ANDREA, Stanley , ZHENG, Zhizhen Barbara , CONNOLLY, Timothy P. , LANGLEY, David R. , PEESE, Kevin , WANG, Zhongyu , WALKER, Michael A. , KADOW, John F.
IPC分类号: C07D498/16 , A61K31/519 , A61P31/18
CPC分类号: C07D498/22 , A61K31/519 , A61K45/06 , C07D498/16
摘要: The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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4.PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION 审中-公开
标题翻译: 吡啶-3-基乙酸衍生物作为人免疫缺陷病毒复制的抑制剂公开(公告)号:EP3319954A1
公开(公告)日:2018-05-16
申请号:EP16736638.4
申请日:2016-07-07
发明人: KADOW, John F. , NAIDU, B. Narasimhulu , PATEL, Manoj , ROMINE, Jeffrey Lee , ST. LAURENT, Denis R. , WANG, Tao , ZHANG, Zhongxing
IPC分类号: C07D401/04 , A61K31/4545 , A61P31/00 , C07D401/14 , C07D413/14 , C07D417/04
CPC分类号: C07D401/04 , A61P31/18 , C07D401/14 , C07D413/14 , C07D417/04 , C07D417/14
摘要: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS. (I)
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公开(公告)号:EP4038061A1
公开(公告)日:2022-08-10
申请号:EP20797180.5
申请日:2020-10-02
发明人: BOWSHER, Michael S. , PARCELLA, Kyle E. , PATEL, Manoj , GILLIS, Eric P , NAIDU, B. Narasimhulu
IPC分类号: C07D401/14 , C07D403/14 , C07D413/14 , C07D417/14 , A61P31/18 , A61K31/517
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6.PYRAZOLOPYRIMIDINE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION 审中-公开
标题翻译: 吡唑并嘧啶 - 咪唑啉酮抑制剂替代物公开(公告)号:EP3152215A1
公开(公告)日:2017-04-12
申请号:EP15709382.4
申请日:2015-02-13
发明人: NAIDU, B. Narasimhulu , WANG, Tao , PEESE, Kevin , YIN, Zhiwei , ZHANG, Zhongxing , KADOW, John F. , PATEL, Manoj
IPC分类号: C07D498/16 , C07D498/22 , A61K31/519 , A61P31/18
CPC分类号: C07D498/16 , A61K31/519 , A61K45/06 , C07D498/22
摘要: The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
摘要翻译: 本发明一般涉及式I化合物,包括用于治疗人类免疫缺陷病毒(HIV)感染的组合物和方法。 本公开提供了HIV整合酶的新型抑制剂,含有这些化合物的药物组合物,以及使用这些化合物治疗HIV感染的方法。
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7.FUSED PYRIMIDINES AS INHIBITORS OF IMMUNODEFICIENCY VIRUS REPLICATION 有权
标题翻译: KENENSIERTE PYRIMIDINE ALS INHIBITOREN DER IMMUNDEFIZIENZVIRUSREPLIKATION公开(公告)号:EP2822949B9
公开(公告)日:2017-01-25
申请号:EP13710240.6
申请日:2013-03-04
发明人: PENDRI, Annapurna , LANGLEY, David R. , GERRITZ, Samuel , LI, Guo , ZHAI, Weixu , D'ANDREA, Stanley , PATEL, Manoj , NAIDU, B. Narasimhulu , PEESE, Kevin , WANG, Zhongyu
IPC分类号: C07D487/04 , A61P31/18 , A61K31/519
CPC分类号: C07D487/04 , C07D498/08 , C07D519/00
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公开(公告)号:EP3870576A1
公开(公告)日:2021-09-01
申请号:EP19794682.5
申请日:2019-10-22
发明人: BOWSHER, Michael S. , GILLIS, Eric P , IWUAGWU, Christiana , PARCELLA, Kyle E. , PATEL, Manoj , WANG, Alan Xiangdong
IPC分类号: C07D403/14 , A61P31/18 , A61K31/517
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公开(公告)号:EP3870575A1
公开(公告)日:2021-09-01
申请号:EP19794679.1
申请日:2019-10-22
IPC分类号: C07D403/14 , A61P31/18 , A61K31/517
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10.
公开(公告)号:EP3107908B1
公开(公告)日:2019-03-27
申请号:EP15709381.6
申请日:2015-02-12
发明人: NAIDU, B. Narasimhulu , PATEL, Manoj , ROMINE, Jeffrey Lee , ST. LAURENT, Denis R. , WANG, Tao , ZHANG, Zhongxing , KADOW, John F.
IPC分类号: C07D401/14 , C07D413/14 , C07D401/04 , C07D409/14 , C07D417/14 , C07D213/61 , A61K31/4545 , A61P31/18
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