公开(公告)号：EP1747056B1

公开(公告)日：2018-09-26

申请号：EP05714053.5

申请日：2005-02-23

申请人： VITAL THERAPIES, INC.

发明人： HE, Dar ,  BROTHERTON, John, D.

IPC分类号： A61M1/34

CPC分类号： A61M1/3472 ,  A61M1/1694 ,  A61M1/1698 ,  A61M1/3475 ,  A61M1/3489

摘要： An extracorporeal filtration and detoxification system and method generally comprise separating ultrafiltrate from cellular components of blood, treating the ultrafiltrate independently of the cellular components in a recirculation circuit, recombining treated ultrafiltrate and the cellular components, and returning whole blood to the patient. A recirculation circuit generally comprises an active cartridge including active cells operative to effectuate a selected treatment; in some embodiments, the active cells are the C3A cell line.

公开(公告)号：EP1747056A2

公开(公告)日：2007-01-31

申请号：EP05714053.5

申请日：2005-02-23

申请人： VITAL THERAPIES, INC.

发明人： HE, Dar ,  BROTHERTON, John, D.

IPC分类号： B01D61/20

CPC分类号： A61M1/3472 ,  A61M1/1694 ,  A61M1/1698 ,  A61M1/3475 ,  A61M1/3489

摘要： An extracorporeal filtration and detoxification system and method generally comprise separating ultrafiltrate from cellular components of blood, treating the ultrafiltrate independently of the cellular components in a recirculation circuit, recombining treated ultrafiltrate and the cellular components, and returning whole blood to the patient. A recirculation circuit generally comprises an active cartridge including active cells operative to effectuate a selected treatment; in some embodiments, the active cells are the C3A cell line.

摘要翻译： 体外过滤和解毒系统和方法通常包括从血液的细胞组分分离超滤液，在再循环回路中独立于细胞组分处理超滤液，重新组合处理的超滤液和细胞组分，并将全血返回给患者。 再循环回路通常包括主动药筒，主动药筒包括可操作以实现选定治疗的活动细胞; 在一些实施方案中，活性细胞是C3A细胞系。