公开(公告)号：EP0374252A4

公开(公告)日：1991-05-08

申请号：EP88908416

申请日：1988-05-26

申请人： VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY I ISPYTATELNY INSTITUT MEDITSINSKOI TEKHNIKI

发明人： AKIMOVA, ALLA YAKOVLEVNA ,  DAVYDOV, ANATOLY BORISOVICH ,  SINEV, JURY VIKTOROVICH ,  SOLOMATIN, ALEXANDR DMITRIEVICH

IPC分类号： A61K9/08 ,  A61K31/275 ,  A61K31/765 ,  A61K31/785 ,  A61K47/08 ,  A61K47/10 ,  A61L24/06 ,  A61P7/04 ,  A61K31/22

CPC分类号： A61K31/765 ,  A61K31/275 ,  A61K31/785 ,  A61L24/06 ,  A61L2400/04 ,  A61L2400/06 ,  A61K2300/00 ,  C08L35/04

摘要： An injection-type hemostatic composition consists of the following components in per cent by weight: ether of alpha-cyanacrylic acid or a mixture of ethers of alpha-cyanacrylic acid 65.0-75.0, monoalkylethers of polyethylene glycol and of simple aliphatic alcohols of the general formula: CnH2n+IO(C2H4O)mH, where n = 10-18, m = 7-10, 0.01-0.02, water-soluble ketone 23.29-31.98, citric acid 1.5-2.5, tannin 0.2-0.5.

公开(公告)号：EP0298121A4

公开(公告)日：1991-01-30

申请号：EP87902189

申请日：1987-01-14

申请人： VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY I ISPYTATELNY INSTITUT MEDITSINSKOI TEKHNIKI ,  MOSKOVSKY NAUCHNO-ISSLEDOVATELSKY ONKOLOGICHESKY INSTITUT IMENI P.A. GERTSENA

发明人： AKIMOVA, ALLA YAKOVLEVNA ,  DAVYDOV, ANATOLY BORISOVICH ,  EGIEV, VALERY NIKOLAEVICH ,  ILIINA, ANNA IVANOVNA ,  KAPUSTIN, JURY PAVLOVICH ,  ORFANIDI, ANESTY KHRISTOVICH ,  SMIRNOV, ALEXEI NIKOLAEVICH ,  STEPANOV, EDUARD ALEXANDROVICH ,  TIMOKHINA, VALERIA IOSIFOVNA ,  CHIGIR, ANATOLY NIKOLAEVICH ,  SCHITKOV, KIRILL GEORGIEVICH

IPC分类号： A61K31/78 ,  A61L24/06 ,  A61L26/00 ,  A61L27/00 ,  A61P17/00 ,  A61P43/00 ,  A61L15/00 ,  A61L15/01

CPC分类号： A61L24/06 ,  A61L26/0014 ,  Y10S623/92 ,  C08L51/06 ,  C08L35/04

摘要： A biocompatible material for treatment of defects in tissues and organs consists of a graft copolymer of alpha-cyanacrylate with the polyacryl acid with a molar mass of 200,000-600,000, obtained by interaction of alpha-cyanacrylate with the polyacryl acid in the presence of a cross-linking agent in the following ratio of the said components in percent by weight: alpha-cyanacrylate - 14-34, polyacryl acid with molar mass of 200,000-600,000 - 15-43, cross-linking agent - 71-23.