公开(公告)号：EP1778740A1

公开(公告)日：2007-05-02

申请号：EP05748637.5

申请日：2005-06-10

申请人： VersaMatrix A/S

发明人： GAVELIN, Patrik ,  REHNBERG, Pehr, Nicola ,  JOHANNSEN, Ib

IPC分类号： C08F8/00 ,  C08F8/28 ,  C08F226/02

CPC分类号： C08F226/02 ,  B01J20/267 ,  B01J20/285 ,  C08J3/12 ,  C08J3/246 ,  C08J2339/02 ,  C08J2371/02

摘要： The present invention relates to the synthesis of a beaded and cross-linked, high loading capacity polymer for solid phase synthesis, purification of reaction mixtures, chromatographic separation procedures, and the like. The invention can thus be used for the isolation of molecular entities having an affinity for the polymer beads or a chemical entity attached thereto. The beaded polymer matrix can be formed by cross-linking an optionally substituted poly(aminoalkylene), under inverse suspension or inverse emulsion polymerisation conditions, with a cross-linking unit of functionality ≥2.

公开(公告)号：EP1794209A1

公开(公告)日：2007-06-13

申请号：EP05774799.0

申请日：2005-08-26

申请人： VersaMatrix A/S

发明人： JOHANNSEN, Ib ,  GAVELIN, Patrik ,  GALLEGO, Monica, Ramos

IPC分类号： C08G65/18

CPC分类号： C08G65/18 ,  C08G65/00 ,  Y10T428/254

摘要： The present invention relates to polyether resins, methods for their manufacture and uses thereof. In one aspect of the invention the polyether resin comprises a plurality of functional groups and is obtained by polymerisation of a mixture of alkoxylated reactive compounds selected from a) alkoxylated compounds having a functionality of more than one, and b) alkoxylated monofunctional reactive compounds, wherein the alkoxylated part of the alkoxylated compounds having a functionality of more than one has an average molecular weight which is different from the average molecular weight of the alkoxylated part of the alkoxylated monofunctional reactive compounds.

公开(公告)号：EP1699553A2

公开(公告)日：2006-09-13

申请号：EP04803060.5

申请日：2004-12-22

申请人： VersaMatrix A/S

发明人： CHRISTENSEN, Soeren, Flygenring ,  JOHANNSEN, Ib

IPC分类号： B01J19/00

CPC分类号： G01N21/645 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00551 ,  C40B70/00 ,  G01N2015/149 ,  G01N2021/6417 ,  G01N2035/00574

摘要： The present invention relates to an apparatus for analysing beads and particles, such as polymer beads used e.g. for solid phase synthesis. The apparatus in one embodiment comprises a rotatable, circular disc comprising a plurality of through-going, inlets, wherein an individual bead from a composition comprising different beads can be fixed to the disc at the end-position of a through-going inlet by applying a pressure drop over said disc comprising said through-going inlets. The pressure drop results in beads being sucked (i.e detachably fixed) onto the disc on top of the through-going inlets. When the disc is rotated the beads are transferred from the position where they initially became attached to the disc to fixed positions wherein suitable devices for measuring and/or analyzing and/or sorting the beads can be operated in order to e.g. measure and/or analyse and/or sort at least one bead of a plurality of beads. More specifically, the invention relates to an apparatus for measuring a plurality of optically detectable beads, such as polymer beads, said apparatus comprising a) a vacuum container comprising at least one planar capture body capable or rotating around a central axis, wherein said capture body comprises a plurality of through-going inlets, and wherein the diameter of each inlet is smaller than the average diameter of the beads to be measured and/or analysed and/or sorted, b) a pressure controlling device capable of controlling the pressure in the vacuum container, c) a device for rotating the vacuum container around the axis of the capture disc, and d) a device for measuring at least one property of at least one bead.

公开(公告)号：EP1784441A1

公开(公告)日：2007-05-16

申请号：EP05774800.6

申请日：2005-08-26

申请人： VersaMatrix A/S

发明人： JOHANNSEN, Ib ,  GAVELIN, Patrik

IPC分类号： C08G65/333 ,  C08G65/322 ,  C08L71/02 ,  C08F8/30

CPC分类号： C08F8/32 ,  C08L71/02 ,  C08L2666/04

摘要： The present invention relates to polymer resins, methods for their generation and uses thereof. In one aspect the present invention is directed to a resin obtainable by aminolysis of a precursor resin, wherein the precursor resin is obtainable by polymerisation of i) polydisperse di-or oligofunctional vinyl or cyclic ether compounds and ii) aminolytically sensitive, mono-functional vinyl or cyclic ether compounds.

公开(公告)号：EP1701784A1

公开(公告)日：2006-09-20

申请号：EP04803061.3

申请日：2004-12-22

申请人： VersaMatrix A/S

发明人： CHRISTENSEN, Soeren, Flygenring ,  JOHANNSEN, Ib ,  CARSTENSEN, Jens, Michael ,  KUHLMANN, Lionel

IPC分类号： B01J19/00 ,  G06K9/64 ,  G01N15/14

CPC分类号： G01N21/6428 ,  B01J19/0046 ,  B01J2219/00468 ,  B01J2219/00576 ,  B01J2219/00596 ,  B01J2219/00689 ,  B01J2219/00695 ,  B01J2219/0072 ,  C40B20/04 ,  C40B50/14 ,  C40B60/10 ,  G01N21/645 ,  G01N21/6458 ,  G06K9/6211

摘要： The present invention is relates to methods for the identification of spatially encoded beaded or granulated matrices comprising a plurality of immobilised particles. The identification is based on a distance matrix determination or based on a set of geometrical figures, such a triangles, on the basis of which individual matrices can be determined.