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1.发明公开
公开(公告)号：EP4347033A1
公开(公告)日：2024-04-10
申请号：EP22740730.1
申请日：2022-06-03
Applicant: Vertex Pharmaceuticals Incorporated
Inventor： BECK, Elizabeth Mary , PULLIN, Robert , ETXEBARRIA JARDI, Gorka , STAMOS, Dean , SCHMIDT, Yvonne , PONTILLO, Joseph , THOMSON, Stephen Andrew , SHAW, David Matthew , AHMAD, Nadia M. , CARVALHO MEIRELES, Lidio Marx , SKERRATT, Sarah , HADIDA RUAH, Sara S. , NEUBERT, Timothy Donald , HURLEY, Dennis James , DURRANT, Steven John , WRAY, Christopher , VIRANI, Anisa Nizarali , NORTH, Kiri , GALAN, Bhairavi , KNEGTEL, Ronald Marcellus , CHUDYK, Ewa Iwona , PINDER, Joanne Louise , SOUSA, Bruno Artur , PIERARD, Francoise
IPC: A61P29/00 , C07D405/12 , A61K31/443
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2.发明公开
公开(公告)号：EP4347584A1
公开(公告)日：2024-04-10
申请号：EP22736099.7
申请日：2022-06-03
Applicant: Vertex Pharmaceuticals Incorporated
Inventor： BECK, Elizabeth, Mary , PULLIN, Robert , ETXEBARRIA JARDI, Gorka , STAMOS, Dean , SCHMIDT, Yvonne , PONTILLO, Joseph , THOMSON, Stephen Andrew , SHAW, David Matthew , AHMAD, Nadia M. , CARVALHO MEIRELES, Lidio Marx , SKERRATT, Sarah , HADIDA RUAH, Sara S. , MILLER, Mark Thomas , NEUBERT, Timothy Donald , HURLEY, Dennis James , ZHOU, Jinglan , KINTZER, Alexander , DURRANT, Steven John , WRAY, Christopher , VIRANI, Anisa Nizarali , NORTH, Kiri , DODD, James , JACQUES, Reece , O'DONNELL, Michael Edward , GALAN, Bhairavi , KNEGTEL, Ronald Marcellus , CHUDYK, Ewa Iwona , PINDER, Joanne Louise , SOUSA, Bruno Artur , STEVENS, Rebecca E.
IPC: C07D405/12 , C07D405/14 , C07D491/048 , A61P29/00 , A61K31/443
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Patent Agency Ranking
公开(公告)号：EP4347583A1
公开(公告)日：2024-04-10
申请号：EP22736097.1
申请日：2022-06-03
Applicant: Vertex Pharmaceuticals Incorporated
Inventor： BECK, Elizabeth Mary , PULLIN, Robert , ETXEBARRIA JARDI, Gorka , STAMOS, Dean , SCHMIDT, Yvonne , PONTILLO, Joseph , THOMSON, Stephen Andrew , SHAW, David Matthew , AHMAD, Nadia M. , CARVALHO MEIRELES, Lidio Marx , SKERRATT, Sarah , HADIDA RUAH, Sara S. , NEUBERT, Timothy Donald , HURLEY, Dennis James , KINTZER, Alexander , DURRANT, Steven John , WRAY, Christopher , VIRANI, Anisa Nizarali , NORTH, Kiri , JACQUES, Reece , GEDDIS, Stephen Michael , GALAN, Bhairavi , KNEGTEL, Ronald Marcellus , CHUDYK, Ewa Iwona , PINDER, Joanne Louise , SOUSA, Bruno Artur , FRAYSSE, Damien , MUI, James Jun Bon , AUSTIN, James Robert , STORCK, Pierre-Henri
IPC: C07D405/12 , C07D405/14 , C07D493/10 , C07D413/14 , C07D471/04 , C07D471/08 , C07D487/10 , C07D491/048 , C07D491/08 , C07D491/10 , C07D498/04 , C07D498/08 , A61K31/443 , A61K31/497 , A61P29/00
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公开(公告)号：EP4506001A2
公开(公告)日：2025-02-12
申请号：EP24200855.5
申请日：2020-12-04
Applicant: Vertex Pharmaceuticals Incorporated
Inventor： DURRANT, Steven, John , AHMAD, Nadia , BECK, Elizabeth, Mary , CARVALHO MEIRELES, Lidio , CHUDYK, Ewa, Iwona , ETXEBARRIA JARDI, Gorka , GALAN, Bhairavi , HADIDA RUAH, Sara, S. , HURLEY, Dennis, James , KNEGTEL, Ronald, Marcellus , NEUBERT, Timothy, Donald , PINDER, Joanne, Louise , PONTILLO, Joseph , PULLIN, Robert , SCHMIDT, Yvonne , SHAW, David, Matthew , SKERRATT, Sarah , STAMOS, Dean , THOMSON, Stephen, Andrew , VIRANI, Anisa, Nizarali , WRAY, Christopher
IPC: A61K31/443
Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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公开(公告)号：EP4347032A1
公开(公告)日：2024-04-10
申请号：EP22740629.5
申请日：2022-06-03
Applicant: Vertex Pharmaceuticals Incorporated
Inventor： BECK, Elizabeth Mary , PULLIN, Robert , ETXEBARRIA JARDI, Gorka , STAMOS, Dean , SCHMIDT, Yvonne , PONTILLO, Joseph , THOMSON, Stephen Andrew , SHAW, David Matthew , AHMAD, Nadia M. , CARVALHO MEIRELES, Lidio Marx , SKERRATT, Sarah , HADIDA RUAH, Sara S. , MILLER, Mark Thomas , NEUBERT, Timothy Donald , HURLEY, Dennis James , ZHOU, Jinglan , KINTZER, Alexander , DURRANT, Steven John , WRAY, Christopher , VIRANI, Anisa Nizarali , NORTH, Kiri , DODD, James , JACQUES, Reece , GEDDIS, Stephen Michael , GALAN, Bhairavi , KNEGTEL, Ronald Marcellus , CHUDYK, Ewa Iwona , PINDER, Joanne Louise , SOUSA, Bruno Artur , STEVENS, Rebecca E. , WRIGHT, Miranda Adele , TWIN, Heather Clare , MUI, James Jun Bon
IPC: A61P29/00 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D471/08 , C07D487/08 , C07D491/052 , C07D491/08 , C07D491/10 , C07D498/04 , C07D521/00 , A61K31/443
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6.发明公开
公开(公告)号：EP4347031A1
公开(公告)日：2024-04-10
申请号：EP22740607.1
申请日：2022-06-03
Applicant: Vertex Pharmaceuticals Incorporated
Inventor： BECK, Elizabeth, Mary , PULLIN, Robert , ETXEBARRIA JARDI, Gorka , STAMOS, Dean , SCHMIDT, Yvonne , PONTILLO, Joseph , THOMSON, Stephen Andrew , SHAW, David Matthew , AHMAD, Nadia M. , CARVALHO MEIRELES, Lidio Marx , SKERRATT, Sarah , HADIDA RUAH, Sara S. , NEUBERT, Timothy Donald , HURLEY, Dennis James , ZHOU, Jinglan , DURRANT, Steven John , WRAY, Christopher , VIRANI, Anisa Nizarali , NORTH, Kiri , DODD, James , O'DONNELL, Michael Edward , GALAN, Bhairavi , KNEGTEL, Ronald Marcellus , CHUDYK, Ewa Iwona , PINDER, Joanne Louise
IPC: A61P29/00 , C07D405/12 , A61K31/443
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公开(公告)号：EP4069691A1
公开(公告)日：2022-10-12
申请号：EP20825397.1
申请日：2020-12-04
Applicant: Vertex Pharmaceuticals Incorporated
Inventor： DURRANT, Steven, John , AHMAD, Nadia , BECK, Elizabeth, Mary , CARVALHO MEIRELES, Lidio , CHUDYK, Ewa, Iwona , ETXEBARRIA JARDI, Gorka , GALAN, Bhairavi , HADIDA RUAH, Sara, S. , HURLEY, Dennis, James , KNEGTEL, Ronald, Marcellus , NEUBERT, Timothy, Donald , PINDER, Joanne, Louise , PONTILLO, Joseph , PULLIN, Robert , SCHMIDT, Yvonne , SHAW, David, Matthew , SKERRATT, Sarah , STAMOS, Dean , THOMSON, Stephen, Andrew , VIRANI, Anisa, Nizarali , WRAY, Christopher
IPC: C07D405/12 , C07D405/14 , A61P29/00 , A61K31/443
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