公开(公告)号：EP4186562A1

公开(公告)日：2023-05-31

申请号：EP21210650.4

申请日：2021-11-26

申请人： Vilnius University ,  National Cancer Institute

发明人： Gaubas, Eugenijus ,  Ceponis, Tomas ,  Pukas, Kornelijus ,  Rumbauskas, Vytautas ,  Uzgiryte, Milita ,  Venius, Jonas ,  Akelaitis, Kestutis ,  Cicinas, Aleksandras

IPC分类号： A61N5/10

摘要： This invention discloses a system and self-consistent method for brachytherapy procedure planning and verification. Those are based on instantaneous 3D-positioning of radionuclide emitters (5) and spatial 3D-dosimetry in a brachytherapy phantom (1), before brachytherapy in-vivo treatment. Spatial positioning and dosimetry are performed by the triangulation technique using needle-type probes being fixed in time-space-resolved coordinates, thus operating as 3D-scanner. The system (2) comprises a base-plate (10) with mesh-work (21), a plurality of catheter-installation grooves (20), and at least three needle-type scaling catheters (6) with probes internally comprising scintillator-sensors (3) as optical beacons, and dosimeters (4). The catheter (6) probes are positioned within the phantom (1) for brachytherapy planning and verification. The coordinates of 3D-scanner (3-9) are tightly linked to the base-plate (10) and the installation grooves (20) of the phantom (1) via marked labels and by RPVD means. The invention facilitates the brachytherapy planning and verification stage, wherein the obtained verification results further can be efficiently applied for brachytherapy in vivo treatment procedure, by increasing spatial precision of the therapeutic dose applied to a patient.