专利检索 ap:("Virobay, Inc.") AND inv:"MOSSMAN, Craig, J." 第 1 页

1.

发明公开
DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS 审中-公开
标题翻译：分离型维生素A

公开(公告)号：EP2262370A1

公开(公告)日：2010-12-22

申请号：EP08744863.5

申请日：2008-04-01

申请人： Virobay, Inc.

发明人： LINK, John, O. , MOSSMAN, Craig, J. , LIU, Jie , WOO, Soon Hyung

IPC分类号： A01N57/00 , A61K31/66

CPC分类号： C07C255/46 , C07C2601/02

摘要： The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S, and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

摘要翻译： 本发明涉及作为半胱氨酸蛋白酶抑制剂，特别是组织蛋白酶B，K，L，F和S的化合物，因此可用于治疗由这些蛋白酶介导的疾病。本发明涉及包含这些化合物的药物组合物及其制备方法。

2.

发明授权
SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS 有权
标题翻译：磺酰胆碱酯酶

公开(公告)号：EP1866277B1

公开(公告)日：2014-06-25

申请号：EP06739439.5

申请日：2006-03-22

申请人： Virobay, Inc.

发明人： MOSSMAN, Craig, J.

IPC分类号： C07C233/00 , C07D211/30 , C07D211/82 , C07D261/06 , A61K31/16 , A61K31/42 , A61K31/44 , A61K31/47

CPC分类号： C07C317/46 , C07C2601/02 , C07C2601/04 , C07D213/32 , C07D213/70 , C07D261/08