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1.发明授权NICKEL CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS 有权含镍的加氢甲硅烷基化催化剂和含有催化剂的组合物
公开(公告)号：EP2758416B1
公开(公告)日：2018-05-09
申请号：EP12775358.0
申请日：2012-09-20
发明人： BRANDSTADT, Kurt , COOK, Simon , NGUYEN, Binh, Thanh , SURGENOR, Avril , TAYLOR, Richard , TZOU, Ming-Shin , DASH, Aswini , OLSEN, Matthew
IPC分类号： C07F15/04
CPC分类号： B01J31/2295 , B01J31/0272 , B01J31/22 , B01J31/24 , B01J31/2414 , B01J31/2433 , B01J37/00 , B01J2231/323 , B01J2531/16 , B01J2531/17 , B01J2531/46 , B01J2531/49 , B01J2531/56 , B01J2531/64 , B01J2531/74 , B01J2531/821 , B01J2531/827 , B01J2531/842 , B01J2531/845 , B01J2531/847 , C07C209/66 , C07C213/08 , C07C217/92 , C07D213/32 , C07D213/38 , C07D213/53 , C07D215/12 , C07D271/06 , C07D295/135 , C07D307/52 , C07D333/22 , C07D413/10 , C07D413/14 , C07F1/00 , C07F1/005 , C07F1/08 , C07F3/06 , C07F7/00 , C07F7/0805 , C07F7/0838 , C07F7/0872 , C07F7/0879 , C07F7/0889 , C07F7/0896 , C07F7/1804 , C07F7/1876 , C07F9/5045 , C07F9/60 , C07F11/005 , C07F13/00 , C07F13/005 , C07F15/0033 , C07F15/0046 , C07F15/02 , C07F15/065 , C08G77/08 , C09K3/00 , G07F13/00
摘要： A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.
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2.发明授权
公开(公告)号：EP2758413B1
公开(公告)日：2018-03-07
申请号：EP12775357.2
申请日：2012-09-20
发明人： BRANDSTADT, Kurt , COOK, Simon , NGUYEN, Binh Thanh , SURGENOR, Avril , TAYLOR, Richard , TZOU, Ming-Shin , DASH, Aswini , OLSEN, Matthew
IPC分类号： C07F15/00 , C07D413/14 , B01J31/22 , B01J31/24 , C07D215/12 , C07F9/50 , C07F9/60 , C07D333/22 , C07F13/00 , C07C209/66 , C07F15/02 , C07F15/06 , C07D213/08 , C07C217/92 , C07D413/10 , C07D271/06 , C07F1/00 , C07F1/08
CPC分类号： B01J31/2295 , B01J31/0272 , B01J31/22 , B01J31/24 , B01J31/2414 , B01J31/2433 , B01J37/00 , B01J2231/323 , B01J2531/16 , B01J2531/17 , B01J2531/46 , B01J2531/49 , B01J2531/56 , B01J2531/64 , B01J2531/74 , B01J2531/821 , B01J2531/827 , B01J2531/842 , B01J2531/845 , B01J2531/847 , C07C209/66 , C07C213/08 , C07C217/92 , C07D213/32 , C07D213/38 , C07D213/53 , C07D215/12 , C07D271/06 , C07D295/135 , C07D307/52 , C07D333/22 , C07D413/10 , C07D413/14 , C07F1/00 , C07F1/005 , C07F1/08 , C07F3/06 , C07F7/00 , C07F7/0805 , C07F7/0838 , C07F7/0872 , C07F7/0879 , C07F7/0889 , C07F7/0896 , C07F7/1804 , C07F7/1876 , C07F9/5045 , C07F9/60 , C07F11/005 , C07F13/00 , C07F13/005 , C07F15/0033 , C07F15/0046 , C07F15/02 , C07F15/065 , C08G77/08 , C08G77/12 , C08K5/01 , C08K5/56 , C08L83/04 , C09K3/00 , G07F13/00
摘要： A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.
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3.发明授权PROCESS FOR PRODUCTION OF PYRIDYLETHYLTHIO COMPOUNDS, MODIFIED ION EXCHANGERS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF BISPHENOLS 有权生产吡啶基乙基硫醚化合物的方法，改性离子交换剂，其生产方法以及生产双酚的方法
公开(公告)号：EP1686116B1
公开(公告)日：2018-02-14
申请号：EP04770886.2
申请日：2004-07-23
发明人： HAYASHI, Hideto , HAYASHI, Koichi
IPC分类号： C07D213/32 , C07C37/20 , C07C39/16 , B01J31/10 , C07B61/00
CPC分类号： C07C39/16 , C07C37/20 , C07D213/32
摘要： The present invention relates to a process for producing a pyridylethylthio compound which is improved in yield of the pyridylethylthio compound. In a process for producing a pyridylethylthio compound by reacting vinyl pyridine with a sulfur-containing compound, vinyl pyridine used contains a compound represented by the general formula (1): (wherein R 1 and R 2 are any of combination of isopropenyl group and a hydrogen atom, combination of 1-propenyl group and a hydrogen atom, combination of 2-propenyl group and a hydrogen atom, and combination of methyl group and vinyl group), in an amount of not more than 4% by weight.
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4.发明公开
公开(公告)号：EP3131400A1
公开(公告)日：2017-02-22
申请号：EP15780740.5
申请日：2015-04-10
申请人： Dow AgroSciences LLC
发明人： LOSO, Michael R. , GUSTAFSON, Gary D. , KUBOTA, Asako , YAP, Maurice C. , BUCHAN, Zachary A. , STEWARD, Kimberly M. , SULLENBERGER, Michael T. , HOEKSTRA, William J. , YATES, Christopher M.
IPC分类号： A01N43/40 , A61K31/44 , C07D213/16
CPC分类号： C07D401/10 , A01N43/54 , A01N47/02 , A01N53/00 , A61K31/4406 , A61K31/505 , A61K31/506 , A61K45/06 , C07D213/30 , C07D213/32 , C07D213/57 , C07D239/26 , C07D239/34 , A61K2300/00
摘要： The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
摘要翻译： 本发明描述了具有金属酶调节活性的式I化合物，以及治疗由这些金属酶介导的疾病，病症或症状的方法。
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公开(公告)号：EP1644326B1
公开(公告)日：2016-11-02
申请号：EP04737887.2
申请日：2004-06-28
申请人： Merck Canada Inc.
发明人： BAYLY, Christopher , BLACK, Cameron , CRANE, Sheldon , MCKAY, Daniel, J. , OBALLA, Renata , ROBICHAUD, Joel
IPC分类号： C07C311/06 , C07D235/06 , C07C323/62 , C07D231/12 , C07D233/64 , C07D211/20 , C07C323/25 , C07C323/49 , C07C323/60 , C07C323/61 , C07D257/04 , C07C255/29 , C07D213/32 , C07D213/83
CPC分类号： C07D213/83 , C07C255/29 , C07C311/06 , C07C323/25 , C07C323/49 , C07C323/60 , C07C323/61 , C07C323/62 , C07C2601/02 , C07C2601/14 , C07D211/20 , C07D213/32 , C07D231/12 , C07D233/64 , C07D235/06 , C07D257/04
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6.发明公开COBALT CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS 审中-公开钴的氢化硅烷化和有催化剂组合物
公开(公告)号：EP2758417A2
公开(公告)日：2014-07-30
申请号：EP12780328.6
申请日：2012-09-20
发明人： BRANDSTADT, Kurt , COOK, Simon , NGUYEN, Binh, Thanh , SURGENOR, Avril , TAYLOR, Richard , TZOU, Ming-shin , DASH, Aswini , OLSEN, Matthew
IPC分类号： C07F15/06
CPC分类号： B01J31/2295 , B01J31/0272 , B01J31/22 , B01J31/24 , B01J31/2414 , B01J31/2433 , B01J37/00 , B01J2231/323 , B01J2531/16 , B01J2531/17 , B01J2531/46 , B01J2531/49 , B01J2531/56 , B01J2531/64 , B01J2531/74 , B01J2531/821 , B01J2531/827 , B01J2531/842 , B01J2531/845 , B01J2531/847 , C07C209/66 , C07C213/08 , C07C217/92 , C07D213/32 , C07D213/38 , C07D213/53 , C07D215/12 , C07D271/06 , C07D295/135 , C07D307/52 , C07D333/22 , C07D413/10 , C07D413/14 , C07F1/00 , C07F1/005 , C07F1/08 , C07F3/06 , C07F7/00 , C07F7/0809 , C07F7/0849 , C07F7/0867 , C07F7/0872 , C07F7/0879 , C07F7/0889 , C07F7/0896 , C07F7/1844 , C07F7/1864 , C07F7/1868 , C07F7/1876 , C07F9/5045 , C07F9/60 , C07F11/005 , C07F13/00 , C07F13/005 , C07F15/0033 , C07F15/0046 , C07F15/02 , C07F15/065 , C08G77/08 , C09K3/00 , G07F13/00
摘要： A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.
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公开(公告)号：EP2694059A2
公开(公告)日：2014-02-12
申请号：EP12768320.9
申请日：2012-04-04
发明人： DAKSHANAMURTHY, Sivanesan , BROWN, Milton L. , CLARKE, Robert , SHAHJAHAN, Ayesha N. , SMITH, Jacqueline
IPC分类号： A61K31/41 , A61K31/427 , A61K31/426 , C07D403/04 , C07D403/14 , A61P35/00
CPC分类号： A61K31/4439 , A61K31/41 , A61K31/426 , A61K31/427 , A61K31/444 , A61K45/06 , C07D213/32 , C07D401/04 , C07D401/14 , C07D405/14 , C07D417/04 , C07D417/14
摘要： Small molecule inhibitors of XBP1 splicing by IRE1 are provided, as well as methods for their use in treating or preventing cancer (e.g., endocrine resistant breast cancer), diabetes, and obesity.
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8.发明公开IMPROVED PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL-5-(1-SUBSTITUTED)ALKYLPYRIDINES 有权改进方法，制备2-三氟甲基-5-（1-取代）烷基吡啶
公开(公告)号：EP2646416A2
公开(公告)日：2013-10-09
申请号：EP11844184.9
申请日：2011-11-23
申请人： Dow AgroSciences LLC
IPC分类号： C07D213/32
CPC分类号： C07D213/32
摘要： 2-Trifluoromethyl-5-(1-substituted)alkylpyridines are produced efficiently and in high yield from an 4-alkoxy-1,1,1-trifluorobut-3-en-2-one by a condensation and a cyclization reaction. Both reactions are performed in the same nonpolar solvent without isolation and purification of intermediates.
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9.发明公开SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES 审中-公开BY葡萄糖激酶调节蛋白相互作用SULFONYLPIPERAZINDERIVATE对于糖尿病的治疗
公开(公告)号：EP2609081A1
公开(公告)日：2013-07-03
申请号：EP11752398.5
申请日：2011-08-22
申请人： Amgen Inc.
发明人： ASHTON, Kate , BARTBERGER, Michael David , BO, Yunxin , BRYAN, Marian C. , CROGHAN, Michael , FOTSCH, Christopher Harold , HALE, Clarence Henderson , KUNZ, Roxanne Kay , LIU, Longbin , NISHIMURA, Nobuko , NORMAN, Mark H. , PENNINGTON, Lewis Dale , POON, Steve Fong , STEC, Markian Myroslaw , ST. JEAN, David, Joseph, Jr. , TAMAYO, Nuria A. , TEGLEY, Christopher Michael , YANG, Kevin Chao
IPC分类号： C07D213/30 , C07D213/71 , C07D213/74 , C07D231/18 , C07D239/42 , C07D241/04 , C07D277/36 , C07D333/34 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/12 , C07D491/08 , C07D498/08
CPC分类号： C07D333/34 , C07C317/22 , C07D213/30 , C07D213/32 , C07D213/71 , C07D213/72 , C07D213/74 , C07D231/18 , C07D239/42 , C07D241/04 , C07D277/36 , C07D285/135 , C07D295/26 , C07D401/12 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D491/08 , C07D498/08
摘要： The present invention relates to compounds of Formula I, or pharmaceutically acceptable salts thereof, that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diabetes, and other diseases and/or conditions where glucokinase regulatory protein is involved using the compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions that contain the compounds, or pharmaceutically acceptable salts thereof.
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10.发明公开FLUORINATED OXA OR THIA HETEROARYLALKYLSULFIDE DERIVATIVES FOR COMBATING INVERTEBRATE PESTS 有权氟化或OXA硫杂HETEROARYLALKYLSULFIDDERIVATE TO进行战斗脊椎动物害虫
公开(公告)号：EP2501686A1
公开(公告)日：2012-09-26
申请号：EP10775828.6
申请日：2010-11-11
申请人： Merial Limited
发明人： SÖRGEL, Sebastian , PAULINI, Ralph , GROSS, Steffen , BEYER, Carsten , POHLMAN, Matthias , BASTIAANS, Henricus Maria Martinus , RACK, Michael , CULBERTSON, Deborah, L. , ANSPAUGH, Douglas, D. , THOMPSON, Sarah , SALGADO, Vincent
IPC分类号： C07D285/12 , A01N43/824 , A61K31/433 , A61P33/00
CPC分类号： C07D285/12 , A01N43/08 , A01N43/10 , A01N43/22 , A01N43/40 , A01N43/46 , A01N43/50 , A01N43/54 , A01N43/56 , A01N43/58 , A01N43/60 , A01N43/62 , A01N43/647 , A01N43/66 , A01N43/713 , A01N43/72 , A01N43/78 , A01N43/80 , A01N43/82 , C07D207/325 , C07D209/10 , C07D209/12 , C07D213/32 , C07D213/34 , C07D233/66 , C07D235/12 , C07D237/08 , C07D239/20 , C07D249/08 , C07D251/16 , C07D257/04 , C07D261/08 , C07D263/32 , C07D271/06 , C07D277/26 , C07D307/38 , C07D307/40 , C07D307/79 , C07D307/80 , C07D333/18 , C07D333/54 , C07D333/56
摘要： The invention relates to alkylsulfide derivatives compounds of formula I as hererunder depicted or the enantiomers or veterinarily acceptable salts thereof which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to methods for controlling invertebrate pests by using these compounds and to plant propagation material and to agricultural and veterinary compositions comprising said compounds. wherein U, R1, R2, R3U, X, n and p are defined as in the description.
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