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1.发明授权Pharmaceutically acceptable salts of 4'-(9-acridinylamino) methanesulfon-m-anisidide, their production, and pharmaceutical compositions containing such salts 失效4' - （9-吡啶氨基）甲烷磺酰胺，其生产和包含这种盐的药物组合物的药学接受的盐
公开(公告)号：EP0035862B1
公开(公告)日：1984-06-13
申请号：EP81300879.4
申请日：1981-03-03
IPC分类号： C07D219/10 , C07C59/105 , C07H7/02 , C07H11/04 , A61K31/435 , A61K31/70
CPC分类号： C07H7/033 , C07C59/245 , C07D219/10 , C07F9/091 , C07H7/027
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2.发明公开Pharmaceutically acceptable salts of 4'-(9-acridinylamino) methanesulfon-m-anisidide, their production, and pharmaceutical compositions containing such salts 失效4' - （9-吡啶氨基）甲烷磺酰胺，其生产和包含这种盐的药物组合物的药学接受的盐
公开(公告)号：EP0035862A3
公开(公告)日：1981-11-18
申请号：EP81300879
申请日：1981-03-03
IPC分类号： C07D219/10 , C07C59/105 , C07H07/02 , C07H11/04 , A61K31/435 , A61K31/70
CPC分类号： C07H7/033 , C07C59/245 , C07D219/10 , C07F9/091 , C07H7/027
摘要： For use as, inter alia, an anti-neoplastic agent, there is disclosed a compound of the formula:-
wherein X is an acid having a total of from three to six carbon atoms, two to five hydroxy groups and an acidic group selected from-CO 2 H and-OPO 3 H 2 with the proviso that, when the total number of carbon atoms is three or four, the acidic group is -OP0 3 H 2 . These particular salts of 4'-(9- acridinylamino)methanesulfon- m-anisidide remain in solution for a reasonable period and hence permit the use of the compound in this salt form for introduction into a mammal. Also disclosed are the processes for producing the salts and pharmaceutical compositions including the salts.-
3.发明公开Pharmaceutically acceptable salts of 4'-(9-acridinylamino) methanesulfon-m-anisidide, their production, and pharmaceutical compositions containing such salts 失效的4“药学zulassbare盐 - （9-吖啶）甲米茴香胺，它们的制备方法和含有它们的药物组合物。
公开(公告)号：EP0035862A2
公开(公告)日：1981-09-16
申请号：EP81300879.4
申请日：1981-03-03
IPC分类号： C07D219/10 , C07C59/105 , C07H7/02 , C07H11/04 , A61K31/435 , A61K31/70
CPC分类号： C07H7/033 , C07C59/245 , C07D219/10 , C07F9/091 , C07H7/027
摘要： For use as, inter alia, an anti-neoplastic agent, there is disclosed a compound of the formula:-
wherein X is an acid having a total of from three to six carbon atoms, two to five hydroxy groups and an acidic group selected from-CO 2 H and-OPO 3 H 2 with the proviso that, when the total number of carbon atoms is three or four, the acidic group is -OP0 3 H 2 . These particular salts of 4'-(9- acridinylamino)methanesulfon- m-anisidide remain in solution for a reasonable period and hence permit the use of the compound in this salt form for introduction into a mammal. Also disclosed are the processes for producing the salts and pharmaceutical compositions including the salts.摘要翻译： 为了用作除其他外，在抗肿瘤剂，有圆盘游离缺失下式的化合物： -
worin X是总共具有三至六个碳原子的，两个至五个羟基和在酸性酸 从-CO 2 H和-OPO 3 H 2选择条件是，当碳原子的总数目为3或4，酸性基团是-OPO 3 H 2，条件组。 4分钟这些特别的盐 - （9-吖啶）甲磺酰米茴香胺留在一段合理的时间溶液和因此允许在该盐形式使用该化合物的用于引入哺乳动物。 所以光盘游离缺失是生产的盐和药物组合物包括盐的过程。
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