公开(公告)号：EP2177495A1

公开(公告)日：2010-04-21

申请号：EP08792270.4

申请日：2008-08-06

申请人： Wako Pure Chemical Industries, Ltd.

发明人： TAKANO, Daisuke ,  KATO, Tomokazu ,  FUJINAKA, Toshihiro ,  SAKAMOTO, Kazunori

IPC分类号： C07C37/11 ,  C07C37/84 ,  C07C39/12 ,  C07B61/00

CPC分类号： C07C39/12 ,  C07B2200/13 ,  C07C37/11 ,  C07C37/84 ,  C07C2603/42 ,  Y02P20/55

摘要： An object of the present invention is to provide a process for producing high-purity hydroxytriphenylenes in which not only inexpensive raw materials can be used but also no complicated steps of deprotection such as dealkylation, and reduction and the like are necessary, and which is thereby advantageous in industrial production. Also there is provided a novel crystal of 2,3,6,7,10,11-hexahydroxytriphenylene monohydrate, which has satisfactory thermal stability. The process for producing a compound represented by the general formula (2) is characterized by reacting a compound represented by the general formula (1) in the presence of a metal oxide comprising a metal selected from trivalent iron, pentavalent vanadium and hexavalent molybdenum and of a nonvolatile strong acid:

wherein, Rs are each independently a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms or an alkoxy group having 1 to 3 carbon atoms.

摘要翻译： 本发明的目的是提供一种制备高纯度羟基三苯基的方法，其中不仅可以使用廉价的原料，而且不需要复杂的脱保护步骤如脱烷基化和还原等，从而 有利于工业生产。 还提供了具有令人满意的热稳定性的2,3,6,7,10,11-六羟基三亚苯一水合物的新晶体。 由通式（2）表示的化合物的制备方法的特征在于使通式（1）表示的化合物在包含选自三价铁，五价钒和六价钼的金属的金属氧化物存在下反应， 非挥发性强酸：其中，R 5各自独立地为氢原子，卤素原子，碳原子数为1〜3的烷基或碳原子数为1〜3的烷氧基。