公开(公告)号：EP2056844A2

公开(公告)日：2009-05-13

申请号：EP07804796.6

申请日：2007-08-22

申请人： Wockhardt Research Centre

发明人： SINDKHEDKAR, Milind Dattatraya ,  DESAI, Vijaya, Narayan ,  LORIYA, Rajesh, Maganlal ,  PATEL, Mahesh, Vithalbhai ,  TRIVEDI, Bharat, Kalidas ,  BORA, Rajesh, Onkardas ,  DIWAKAR, Santosh, Devidas ,  JADHAV, Ganesh, Rajaram ,  PAWAR, Shivaji, Sampatrao

IPC分类号： A61K31/7048

CPC分类号： C07D493/04

摘要： The present invention provides compounds having antimicrobial activity for preventing and treating diseases caused by microbial infections. Thus, the present invention relates to novel • semi-synthetic 11,12-γ lactone macrolides and ketolides having antimicrobial activity, processes for making compounds as well as pharmaceutical compositions containing said compounds as active ingredients and methods of treating microbial infections with the compounds.