专利检索 ap:("Wyeth") AND inv:"FOBARE, William Floyd" 第 1 页

1.

发明公开
AMINO-5- Ý4- (DIFLUOROMETHOXY) PHENYL¨-5-PHENYLIMIDAZOLONE COMPOUNDS AS INHIBITORS OF THE BETA-SECRETASE (BACE) 审中-公开
标题翻译：氨基-5- Y4（二氟甲氧基）苯基-5- PHENYLIMIDAZOLON化合物作为β-分泌酶抑制剂（BACE）

公开(公告)号：EP1928841A1

公开(公告)日：2008-06-11

申请号：EP06815185.1

申请日：2006-09-22

申请人： Wyeth

发明人： MALAMAS, Michael Sotirios , ERDEI, James Joseph , FOBARE, William Floyd , QUAGLIATO, Dominick Anthony , ANTANE, Schuyler Adam , ROBICHAUD, Albert Jean

IPC分类号： C07D233/88

CPC分类号： C07D233/88 , C07D401/12 , C07D409/12

摘要： The present invention provides a 2-amino-5-[4-(difluoromethoxy)phenyl]-5-3,5-dihydro-phenylimidazol-4-one compound of formula (I) The present invention also provides methods for the use thereof to inhibit ß-secretase (BACE) and treat ß-amyloid deposits and neurofibrillary tangles.