公开(公告)号：EP4406967A1

公开(公告)日：2024-07-31

申请号：EP22871531.4

申请日：2022-06-30

申请人： Xiamen Innobiomax Biotechnology Co., Ltd. ,  Xiamen Innodx Biotech Co., Ltd

发明人： WANG, Haihong ,  KE, Qishen ,  ZOU, Mengwen ,  ZHUANG, Cuizhen ,  LI, Lihua ,  LI, Huiping ,  CHEN, Weibin ,  KE, Shaojun ,  ZHANG, Yifei ,  LIN, Qiumin ,  SONG, Liuwei ,  XIONG, Junhui

IPC分类号： C07K14/72 ,  C07K19/00 ,  G01N33/68

CPC分类号： C12N15/866 ,  G01N33/68 ,  C07K19/00 ,  C12N5/10 ,  C07K14/72

摘要： The present invention provides a recombinant thyroid stimulating hormone receptor protein, a preparation method therefor and an application thereof. The recombinant thyroid stimulating hormone receptor protein comprises a TSHR protein extracellular segment and a TSHR protein intracellular segment. The C-terminus of the TSHR protein extracellular segment is linked to the N-terminus of the TSHR protein intracellular segment. The protein achieves extracellular soluble expression, and is high in purity, high in activity and good in stability.