公开(公告)号：EP1490693A1

公开(公告)日：2004-12-29

申请号：EP03720676.0

申请日：2003-04-04

申请人： Xzillion GmbH & CO.KG

发明人： THOMPSON, Andrew, Hugin ,  HAMON, Christian ,  KUHN, Karsten ,  MEYER, Markus ,  JUERGEN, Schafer ,  NEUMANN, Thomas

IPC分类号： G01N33/68 ,  C12Q1/68 ,  C07K1/13

CPC分类号： G01N33/6848 ,  C07K1/13 ,  G01N33/6851

摘要： Provided is a method for characterising an analyte by matrix assisted laser desorption ionisation (MALDI) mass spectrometry, which method comprises: (a) labelling the analyte with a light-absorbing label that absorbs light at a pre-determined frequency, to form a labelled analyte; (b) embedding the labelled analyte in a matrix formed from at least one compound that absorbs light, to form an embedded labelled analyte; (c) desorbing the embedded labelled analyte by exposing it to light having the pre-determined frequency, to form a desorbed analyte; and (d) detecting the desorbed analyte by mass spectrometry to characterise the analyte.