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公开(公告)号：EP0416804B1
公开(公告)日：1993-05-26
申请号：EP90309439.9
申请日：1990-08-29
发明人： Konno, Yutaka , Katsuma, Masataka
CPC分类号： A61K47/14 , A61K9/0014 , A61K31/18 , A61K47/22
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2.发明公开External preparation containing amusulosin 失效Äusserlichanzuwendende Amusulosin enthaltende Arzneizubereitung。
公开(公告)号：EP0416804A1
公开(公告)日：1991-03-13
申请号：EP90309439.9
申请日：1990-08-29
发明人： Konno, Yutaka , Katsuma, Masataka
CPC分类号： A61K47/14 , A61K9/0014 , A61K31/18 , A61K47/22
摘要： An external preparation, for the treatment of dysuria or lower urinary tract disease, which comprises
1) at least one compound selected from amusulosin and salts thereof;
2) aqueous alcohol, and
3) at least one transdermal absorption promoting agent selected from aliphatic dicarboxylic acid diesters, nicotinic acid esters and isonicotinic acid esters, with or without addition of a terpene.摘要翻译： 一种用于治疗排尿困难或下尿路疾病的外用制剂，其包含1）至少一种选自阿莫苏洛辛及其盐的化合物; 2）含水醇，以及3）至少一种选自脂肪族二羧酸二酯，烟酸酯和异烟酸酯的透皮吸收促进剂，有或无添加萜烯。 ü
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公开(公告)号：EP0037740A2
公开(公告)日：1981-10-14
申请号：EP81301521.1
申请日：1981-04-07
CPC分类号： A61K9/1617 , A61K9/2013 , A61K9/5015
摘要： A solid microdose drug preparation containing particles of microdose drug such as formoterol fumarate or β-methyldigoxin coated with wax. The wax coating considerably improves the stability and the content uniformity of the microdose drug in the preparation.
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公开(公告)号：EP0415671A2
公开(公告)日：1991-03-06
申请号：EP90309318.5
申请日：1990-08-24
发明人： Sonobe, Takashi , Watanabe, Shunsuke , Katsuma, Masataka , Takamatsu, Narushi , Konno, Yutaka , Takagi, Hirokazu
IPC分类号： A61K9/22
CPC分类号： A61K9/0065
摘要： A device for extended retention in the stomach, the device comprising a molding which comprises shape memory material (A) joined to or mixed with material erodible in vivo (B), said molding being of a size, shape and durability to remain in the stomach for a definite residence time.
The device can be of a shape such as not to hinder passage of food in the stomach and is capable of being folded to an orally administrable form. It is used for drug delivery.摘要翻译： 一种用于在胃中延长保留的装置，该装置包括模制件，该模制件包括与体内可侵蚀的物质（B）连接或混合的形状记忆材料（A），所述模制件具有保留在胃中的尺寸，形状和耐久性 确定停留时间。 该装置可以是不妨碍食物在胃中通过并且能够被折叠成可口服的形式的形状。 用于药物输送。
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公开(公告)号：EP0269246A3
公开(公告)日：1988-06-08
申请号：EP87309273
申请日：1987-10-20
IPC分类号： A61N01/30
CPC分类号： A61N1/0448 , A61N1/0436
摘要： A plaster structure for iontophoresis comprising an electrode layer (4) and a medicament-containing layer (1), wherein a water supplying layer - composed of a water-containing lamina (2) and/or a water-containing self-adhesive lamina (3) - is formed between the electrode layer (4) and the medicament-containing layer (1), and further a sealing cover (5) is formed at the outside of the electrode layer (4).
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公开(公告)号：EP0415671B1
公开(公告)日：1995-03-29
申请号：EP90309318.5
申请日：1990-08-24
发明人： Sonobe, Takashi , Watanabe, Shunsuke , Katsuma, Masataka , Takamatsu, Narushi , Konno, Yutaka , Takagi, Hirokazu
IPC分类号： A61K9/22
CPC分类号： A61K9/0065
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公开(公告)号：EP0152281A3
公开(公告)日：1987-04-29
申请号：EP85300822
申请日：1985-02-07
CPC分类号： A61K9/7084 , A61K9/0014 , A61K31/44 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/18 , A61K47/20 , A61K47/26 , Y10S514/947
摘要： A transdermal formulation of nicardipine hydrochloride which comprises [a] a transdermal formulation base compounded with [b] nicardipine hydrochloride dissolved or suspended in a liquid containing a urea and at least one compound selected from propylene glycol, monohydric alcohols having 2 to 4 carbon atoms, lactic acid, thioglycol, middle chain fatty acid glycerides and sorbitan middle chain fatty acid esters. Such formulations give improved percutaneous absorption of the nicardipine hydrochloride. Inclusion in the formulation of crystallizing inhibitor for nicardipine hydrochloride can improve the stability of the formulation.
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公开(公告)号：EP0153200A2
公开(公告)日：1985-08-28
申请号：EP85301163.3
申请日：1985-02-21
CPC分类号： A61K9/7084 , A61K47/44
摘要： This invention provides a medicinal patch comprising a solution or suspension of drug component and penetration enhancer dispersed in a base selected predominantly from cacao butter, isocacao butter and triglycerides of C 12 to C 18 vegetable saturated fatty acids. This patch composition is usually provided in a shallow dish for adhering to the skin.
摘要翻译： 本发明提供一种药片，其包含药物成分和渗透促进剂的溶液或悬浮液，其分散在主要由可可脂，可可豆黄油和C12至C18植物饱和脂肪酸的甘油三酯选择的碱中。 该贴片组合物通常设置在浅盘中以粘附到皮肤上。
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公开(公告)号：EP0269246B1
公开(公告)日：1993-01-27
申请号：EP87309273.8
申请日：1987-10-20
IPC分类号： A61N1/30
CPC分类号： A61N1/0448 , A61N1/0436
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公开(公告)号：EP0415671A3
公开(公告)日：1991-08-21
申请号：EP90309318.5
申请日：1990-08-24
发明人： Sonobe, Takashi , Watanabe, Shunsuke , Katsuma, Masataka , Takamatsu, Narushi , Konno, Yutaka , Takagi, Hirokazu
IPC分类号： A61K9/22
CPC分类号： A61K9/0065
摘要： A device for extended retention in the stomach, the device comprising a molding which comprises shape memory material (A) joined to or mixed with material erodible in vivo (B), said molding being of a size, shape and durability to remain in the stomach for a definite residence time. The device can be of a shape such as not to hinder passage of food in the stomach and is capable of being folded to an orally administrable form. It is used for drug delivery.
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